Skip to main content
SpringerLink
Log in
Birkhäuser

High Throughput Screening for Novel Anti-Inflammatories

  • Book
  • © 2000

Overview

Editors:
  1. Michael Kahn

    1. Department of Pathobiology, SC-38, University of Washington, Seattle, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Progress in Inflammation Research (PIR)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (12 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. Solid phase synthesis: Applications to combinatorial libraries

    • Sharon M. Dankwardt
    Pages 1-17

  3. Proteasome inhibitors

    • Mohamed A. Iqbal, Mark A. Ator
    Pages 19-34

  4. Caspase-1 (ICE) and other caspases as drug discovery targets: Opportunities and progress

    • Tariq Ghayur, Sheryl J. Hays, Robert V. Talanian
    Pages 35-48

  5. Elastase inhibitors

    • William A. Metz, Norton P. Peet
    Pages 49-85

  6. A high throughput assay for the TNF converting enzyme

    • M. Anthony Leesnitzer, D. Mark Bickett, Marcia L. Moss, J. David Becherer
    Pages 87-100

  7. Tryptase inhibitors

    • Kenneth D. Rice, William R. Moore
    Pages 101-121

  8. Selectin antagonists

    • Falguni Dasgupta
    Pages 123-144

  9. Cell adhesion integrins as pharmaceutical targets

    • Kerry W. Fowler, David T. Crowe
    Pages 145-163

  10. Inhibitors of the MAPK pathway

    • Brion W. Murray, Yoshitaka Satoh, Bernd Stein
    Pages 165-191

  11. Inhibition of NF-кB

    • Mark J. Suto, Anthony M. Manning
    Pages 193-204

  12. IL-1 antagonist discovery

    • Terry L. Bowlin, Stephen D. Yanofsky, Herman Schreuder
    Pages 205-222

  13. Phosphodiesterase inhibitors for respiratory diseases

    • Mark A. Giembycz
    Pages 223-253

  14. Back Matter

    Pages 255-258
    Download chapter PDF
Back to top

Keywords

About this book

Combinatorial chemistry in conjunction with High Throughput Screening (HTS) is revolutionizing the drug discovery process. Yet, we have much to learn about the integration of these powerful techniques with information from genomics, proteomics, computation and pharmacokinetics before dramatic increases in the drug discovery/development processes can be achieved. The chapters in this book represent the state of the art regarding the integration of combinatorial chemistry and HTS in connection with anti-inflammatory targets. Obviously, there is much work to be done beyond what is described in this text, nevertheless, it should set the stage for creative thinking among scientists of many disciplines for the accomplishment of our ultimate goals in treating inflammatory diseases.

Editors and Affiliations

  • Department of Pathobiology, SC-38, University of Washington, Seattle, USA

    Michael Kahn

Bibliographic Information

  • Book Title: High Throughput Screening for Novel Anti-Inflammatories

  • Editors: Michael Kahn

  • Series Title: Progress in Inflammation Research

  • DOI: https://doi.org/10.1007/978-3-0348-8462-4

  • Publisher: Birkhäuser Basel

  • eBook Packages: Springer Book Archive

  • Copyright Information: Birkhäuser Verlag 2000

  • Hardcover ISBN: 978-3-7643-5912-6Published: 01 May 2000

  • Softcover ISBN: 978-3-0348-9578-1Published: 01 November 2012

  • eBook ISBN: 978-3-0348-8462-4Published: 06 December 2012

  • Series ISSN: 1422-7746

  • Series E-ISSN: 2296-4525

  • Edition Number: 1

  • Number of Pages: XI, 258

  • Topics: Molecular Medicine, Pharmacology/Toxicology

Publish with us

Policies and ethics

Back to top

Search

Navigation