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Birkhäuser

Modern Immunosuppressives

  • Book
  • © 2001

Overview

Editors:
  1. Henk-Jan Schuurman

    1. Novartis Pharma AG, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Gilles Feutren

    1. Novartis Pharma AG, Basel, Switzerland

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    You can also search for this editor in PubMed   Google Scholar

  3. Jean-François Bach

    1. Immunologie Clinique, Hôpital Necker, Paris Cedex 15, France

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Milestones in Drug Therapy (MDT)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xii
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  2. Introduction, global perspectives and history of immunosuppression

    1. Introduction, global perspectives and history of immunosuppression

      • Roy Caine, David J. G. White
      Pages 1-7

  3. Immunosuppressive drugs

    1. Front Matter

      Pages 9-9
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    2. Cyclosporine: role of pharmacokinetics

      • Gary A. Levy, Gerard F. Murphy, Paul A. Keown
      Pages 11-28

    3. Tacrolimus

      • Suphamai Bunnapradist, Gabriel Danovitch
      Pages 29-41

    4. The potential role of immunosuppressive macrocyclic lactones

      • Johnny C. Hong, Barry D. Kahan
      Pages 43-75

    5. Inosine monophosphate dehydrogenase inhibition: mycophenolate mofetil

      • Christophe Legendre, Eric Thervet
      Pages 77-96

  4. Biologicals

    1. Front Matter

      Pages 97-97
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    2. Therapeutic anti-T-cell monoclonal antibodies

      • Lucienne Chatenoud, Jean-François Bach
      Pages 99-113

    3. Targeting the IL-2 receptor with antibodies or chimeric toxins

      • Terry B. Strom
      Pages 115-122

  5. New avenues in immunosuppression

    1. Front Matter

      Pages 123-123
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    2. Emerging therapeutic strategies for the prevention and treatment of chronic allograft rejection

      • Pekka Häyry, Hanna Savolainen, Serdar Yilmaz, Einari Aavik
      Pages 125-148

    3. Tolerance induction

      • Stuart J. Knechtle, Majed M. Hamawy
      Pages 149-168

    4. Gene therapy approaches to immunosuppression

      • Reto A. Gadient, Thomas Bühler, Marcel Luyten, N. Rao Movva
      Pages 169-180

  7. Back Matter

    Pages 215-218
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Keywords

About this book

Expanding from the classic use of immunosuppressants in transplantation and rejection, this current overview highlights their new roles in clinical medicine. Immunosuppressants are at the forefront of new treatment modalities. Individual chapters focus on their use not only in prevention or treatment of transplant rejection, but also on their use in immune-complex and autoimmune diseases, including rheumatoid arthritis; on combination therapies to achieve synergy in immunosuppression; on new drugs, low molecular weight chemicals, the use of antibodies and gene therapy; on immunological tolerance to prevent or inhibit transplant rejection; and how data derived from transplant studies can be applied to other avenues of immunosuppression. Clinicians and researchers will appreciate the scope of the work and the presentation of new approaches in the rapidly developing field of immunosuppression.

Editors and Affiliations

  • Novartis Pharma AG, USA

    Henk-Jan Schuurman

  • Novartis Pharma AG, Basel, Switzerland

    Gilles Feutren

  • Immunologie Clinique, Hôpital Necker, Paris Cedex 15, France

    Jean-François Bach

Bibliographic Information

  • Book Title: Modern Immunosuppressives

  • Editors: Henk-Jan Schuurman, Gilles Feutren, Jean-François Bach

  • Series Title: Milestones in Drug Therapy

  • DOI: https://doi.org/10.1007/978-3-0348-8352-8

  • Publisher: Birkhäuser Basel

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Basel AG 2001

  • Hardcover ISBN: 978-3-7643-5981-2Published: 01 June 2001

  • Softcover ISBN: 978-3-0348-9530-9Published: 05 November 2012

  • eBook ISBN: 978-3-0348-8352-8Published: 06 December 2012

  • Series ISSN: 2296-6056

  • Series E-ISSN: 2296-6064

  • Edition Number: 1

  • Number of Pages: XII, 218

  • Topics: Medicine/Public Health, general

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