Mind over Matter - Regulation of Peripheral Inflammation by the CNS

1. Front Matter

   Pages i-ix

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2. Central nervous system and inflammation

   1. Front Matter

      Pages 1-1

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   2. The brain and the mind — can the immune system help?

      • Michal Schwartz

      Pages 3-18

   3. Influence of brain-derived cytokines on the immune response

      • Christian Woiciechowsky, Hans-Dieter Volk

      Pages 19-33

3. Stress and inflammation

   1. Front Matter

      Pages 35-35

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   2. Physical stress/exercise and the immune response

      • Suzi Hong, Paul J. Mills

      Pages 37-56

   3. Pain and immunosuppression

      • Gayle G. Page

      Pages 57-68

4. Sympathetic nervous system

   1. Front Matter

      Pages 69-69

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   2. The sympathetic-immune interface: role in immune regulation and pathology

      • Ilia J. Elenkov

      Pages 71-87

   3. Functional role of the peripheral sympathetic nervous system in inflammatory pain

      • Waltraud Binder

      Pages 89-99

5. Peripheral nervous system and inflammation

   1. Front Matter

      Pages 101-101

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   2. Nerve injury and immune response

      • Claudia Sommer

      Pages 103-120

   3. Neuronal mechanisms of the recruitment of opioid peptide expressing immune cells

      • Shaaban A. Mousa

      Pages 121-136

   4. Peripheral analgesic and anti-inflammatory effects of opioids — neuro-immune crosstalk

      • Halina Machelska, Christoph Stein

      Pages 137-148

   5. The skin as a model for the immunodulatory effects of corticotropin-releasing hormone

      • Andrzej Slominski, Jacobo Wortsman, Elizabeth Linton, Alexander Pisarchik, Blazej Zbytek

      Pages 149-176

   6. Adenosine — A peripheral neuronal modulator of pain and inflammation

      • Jana Sawynok

      Pages 177-199

6. Back Matter

   Pages 201-206

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Several new developments in the field of neuroimmunology with focus on the brain-to-immune system communication have been the incentive for this PIR volume. It covers topics such as brain-immune interactions, the impact of stress on the immune response, pain and immunosuppression, the modulation of inflammation and pain by the sympathetic nervous system, consequences of nerve injury for the immune system, neuronal mechanisms of immune cell recruitment, and the modulation of the immune response by corticotropin-releasing hormone or adenosine. The authors are a unique group of scientists who are all interested in brain-to-immune interactions; however, each from a different perspective. The volume will serve both neurobiologists and immunologists to understand the influence of the central nervous system on peripheral inflammation. Many aspects of this book will also be stimulating for researchers in the pain field.

• CNS
• Nervous System
• Opioid
• adenosine
• brain
• cytokine
• cytokines
• immune response
• immune system
• immunosuppression
• inflammation
• influence
• pain
• pathology
• regulation

• Campus Benjamin Franklin Klinik für Anästhesiologie und operative Intensivmedizin, Charité - Universitätsmedizin Berlin, Berlin, Germany

  Michael Schäfer, Christoph Stein

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