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Table of contents (9 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Following an opening chapter by the late Susumu Ohno on paralogues of sex-determining genes, the five best-studied genes essential for early mammalian gonadal development are portrayed in detail: SF-1 and WT1 and their roles in early events in gonadal development, SRY and SOX9 in testis determination, and the anti-testis gene DAX-1. Subsequent chapters look at the roles of these genes in sex determination in marsupial mammals, birds, reptiles, amphibians and fish, and review the different sex-determining mechanisms, genetic and environmental, that operate in these different vertebrate classes. Two insights emerge: one, that the same basic set of genes appears to operate during early gonadal development in all vertebrates, despite the differences in mechanisms; the other, that sex determination in vertebrates results from a complex network of regulatory interactions and not from a simple hierarchical cascade of gene actions.
Editors and Affiliations
Bibliographic Information
Book Title: Genes and Mechanisms in Vertebrate Sex Determination
Editors: Gerd Scherer, Michael Schmid
Series Title: Experientia Supplementum
DOI: https://doi.org/10.1007/978-3-0348-7781-7
Publisher: Birkhäuser Basel
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eBook Packages: Springer Book Archive
Copyright Information: Springer Basel AG 2001
Softcover ISBN: 978-3-0348-7783-1Published: 03 October 2013
eBook ISBN: 978-3-0348-7781-7Published: 17 April 2013
Series ISSN: 1664-431X
Series E-ISSN: 2504-3692
Edition Number: 1
Number of Pages: XII, 205
Number of Illustrations: 36 b/w illustrations
Topics: Animal Genetics and Genomics, Vertebrates