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Oxidative Stress and Aging

  • Conference proceedings
  • © 1995

Overview

Editors:
  1. R. G. Cutler

    1. Gerontology Research Center, National Institute on Aging, NIH, Baltimore, USA

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  2. L. Packer

    1. Dept. Molecular and Cell Biology, 251 Life Science Addition, Membrane Bioenergetics Group, Berkeley, USA

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  3. J. Bertram

    1. Cancer Research Center of Hawaii, Molecular Oncology, University of Hawaii at Manoa, Honolulu, USA

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  4. A. Mori

    1. Dept. of Neuroscience, Institute of Cellular and Molecular Medicine, Okayama University, Okayama 700, Japan

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Part of the book series: Molecular and Cell Biology Updates (MCBU)

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Table of contents (36 papers)

  1. Front Matter

    Pages I-XII
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  3. Oxidative stress and cellular senescence

    1. Oxidative stress and apoptosis

      • A. F. G. Slater, S. Orrenius
      Pages 21-26

    2. Superoxide and hydrogen peroxide as cellularly generated life-signals in the balance between proliferation and cell death

      • R. H. Burdon
      Pages 27-33

    3. Cellular aging and oxidative stress

      • M. Matsuo, H. Yuan, S. Honda
      Pages 35-43

    4. Cellular nitrogen oxide production: Its role in endogeneous mutation and carcinogenesis

      • R. V. Cooney, L. J. Mordan
      Pages 45-52

    5. Vascular smooth muscle cell proliferation is controlled by d-α-tocopherol at the level of protein kinase C and of the transcription factor AP-1

      • A. Azzi, D. Boscoboinik, D. Marilley, N. K. Özer, B. Stäuble, A. Tasinato
      Pages 53-62

  4. Genetic stability and damage: DNA repair

    1. DNA damage and epigenetic mechanisms of aging

      • R. Holliday
      Pages 63-67

    2. Formation of 8-hydroxyguanine in DNA by aging and oxidative stress

      • T. Hirano, Y. Homma, H. Kasai
      Pages 69-76

    3. Age-dependent DNA modifications (I-compounds): Effects of carcinogenesis and oxidative stress

      • K. Randerath, J. Chang, E. Randerath
      Pages 77-87

    4. Iron-induced carcinogenesis in experimental animals: A free radical mechanism of DNA damage and carcinogenesis

      • S. Okada, S. Hamazaki, T. Akiyama, M. Liu
      Pages 89-99

    5. DNA repair, oxidative stress and aging

      • V. A. Bohr, F. Larminat, B. G. Taffe
      Pages 101-110

  6. Proteins and lipid oxidation

    1. Novel approaches toward inhibition of the Maillard reaction in vivo: Search, isolation and characterization of prokaryotic enzymes which degrade glycated substrates

      • V. M. Monnier, C. Gerhardinger, M. S. Marion, S. Taneda
      Pages 141-149

    2. Age-associated changes of oxidative modification and turnover of proteins

      • S. Goto, A. Hasegawa, H. Nakamoto, A. Nakamura, R. Takahashi, I. V. Kurochkin
      Pages 151-158

  7. Mitochondria

    1. Mitochondria, free radicals, neurodegeneration and aging

      • A. H. V. Schapira
      Pages 159-169

    2. Free radicals and muscle damage due to immobilization of old animals: Effect of growth hormone

      • A. Z. Reznick
      Pages 171-178

    3. PCR analysis of mitochondrial DNA from normal and transgenic glutathione peroxidase mice

      • P. J. Singh, J. Legault, A. Tremblay, P. Julien, M. R. Ven Murthy, M.-E. Mirault
      Pages 179-190
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Keywords

About this book

Oxidative stress and aging Over the past several years there has been an extraordinarily rapid growth in our knowledge of free radical chemistry and its possible involvement in both normal essential biology and age­ related disease and dysfunction. Much of this growth in the traditionally separate sciences of chemistry and molecular gerontology occurred independently, with little interaction or communi­ cation between the scientists working in these two fields. In view of the growing maturity of the two fields and the potential importance of advancing our knowledge in the area of oxidative stress and aging, we perceived a critical need to organize an international conference the "First Inter­ national Conference on Oxidative Stress and Aging" in Hawaii in 1994 to bring together the world's leading scientists in the fields of reactive oxygen species and molecular gerontology. The objective of this conference was to provide a unique opportunity for scholars working in these two related and rapidly growing fields to participate in the exchange, integration, and synthesis of new concepts and ideas, to engage in constructive criticism and to initiate new collaborative research projects. The conference focused on the molecular and cellular aspects of aging as related to oxidative stress. It was one of the largest and most comprehensive international conferences held in molecular gerontology. At this conference a call was made for submission of papers to be used in the publication of a book covering the major contributions of the meeting.

Editors and Affiliations

  • Gerontology Research Center, National Institute on Aging, NIH, Baltimore, USA

    R. G. Cutler

  • Dept. Molecular and Cell Biology, 251 Life Science Addition, Membrane Bioenergetics Group, Berkeley, USA

    L. Packer

  • Cancer Research Center of Hawaii, Molecular Oncology, University of Hawaii at Manoa, Honolulu, USA

    J. Bertram

  • Dept. of Neuroscience, Institute of Cellular and Molecular Medicine, Okayama University, Okayama 700, Japan

    A. Mori

Bibliographic Information

  • Book Title: Oxidative Stress and Aging

  • Editors: R. G. Cutler, L. Packer, J. Bertram, A. Mori

  • Series Title: Molecular and Cell Biology Updates

  • DOI: https://doi.org/10.1007/978-3-0348-7337-6

  • Publisher: Birkhäuser Basel

  • eBook Packages: Springer Book Archive

  • Copyright Information: Birkhäuser Verlag, Basel, Switzerland 1995

  • Softcover ISBN: 978-3-0348-7339-0Published: 29 March 2012

  • eBook ISBN: 978-3-0348-7337-6Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 399

  • Topics: Cell Biology, Internal Medicine, Biochemistry, general

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