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Toward a Molecular Basis of Alcohol Use and Abuse

  • Book
  • © 1994

Overview

Editors:
  1. B. Jansson

    1. Department of Psychiatry, Karolinska Institutet, Huddinge University Hospital, Huddinge, Sweden

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  2. H. Jörnvall

    1. Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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  3. U. Rydberg

    1. Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden

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  4. L. Terenius

    1. Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden

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  5. B. L. Vallee

    1. Center for Biochemical and Biophysical Sciences and Medicine, Harvard Medical School, Boston, USA

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Part of the book series: Experientia Supplementum (EXS, volume 71)

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Table of contents (39 chapters)

  1. Front Matter

    Pages I-X
    Download chapter PDF

  2. Perspectives

    1. Alcohol in human history

      • Bert L. Vallee
      Pages 1-8

  3. Neuropharmacological aspects

    1. Reward and its control by dynorphin peptides

      • Lars Terenius
      Pages 9-17

    2. Adaptation of signal transduction in brain

      • C. Alling, L. Gustavsson, C. Larsson, C. Lundqvist, D. Rodriguez, P. Simonsson
      Pages 19-28

    3. Protein kinase C and adaptation to ethanol

      • R. Roivainen, B. Hundle, R. O. Messing
      Pages 29-38

    4. Molecular control of neuronal survival in the chick embryo

      • Stefano Biffo, Georg Dechant, Hitoshi Okazawa, Yves-Alain Barde
      Pages 39-48

    5. Effects of alcohol on gene expression in neural cells

      • Norbert Wilke, Michael Sganga, Steven Barhite, Michael F. Miles
      Pages 49-59

    6. The role of the NMDA receptor in ethanol withdrawal

      • Paula L. Hoffman, Boris Tabakoff
      Pages 61-70

    7. Molecular diversity of glutamate receptors and their physiological functions

      • S. Nakanishi, M. Masu, Y. Bessho, Y. Nakajima, Y. Hayashi, R. Shigemoto
      Pages 71-80

    8. Multiple dopamine receptors: The D3 receptor and actions of substances of abuse

      • J.-C. Schwartz, J. Diaz, N. Griffon, D. Levesque, M.-P. Martres, P. Sokoloff
      Pages 81-92

    9. Molecular pharmacology of serotonin receptors

      • Paul R. Hartig
      Pages 93-102

    10. Alcohol, the reward system and dependence

      • G. F. Koob, S. Rassnick, S. Heinrichs, F. Weiss
      Pages 103-114

  4. Biological markers and special clinical features

    1. Clinical aspects on molecular probes, markers and metabolism

      • Ulf Rydberg
      Pages 115-120

    2. Familial alcoholism: Family, twin adoption and high risk studies

      • Joachim Knop
      Pages 121-131

    3. Association strategies in substance abuse

      • George R. Uhl
      Pages 133-141

    4. PET-determination of benzodiazepine receptor binding in studies on alcoholism

      • Lars Farde, Stefan Pauli, Jan-Eric Litton, Christer Halldin, Jack Neiman, Göran Sedvall
      Pages 143-153

    5. Serotonin, violent behavior and alcohol

      • Markku Linnoila, Matti Virkkunen, Theodore George, Michael Eckardt, James D. Higley, David Nielsen et al.
      Pages 155-163

    6. Neuropeptides and alcohol addiction in monkeys

      • J. M. van Ree, M. Kornet, C. Goosen
      Pages 165-174

    7. The role of adenosine in mediating cellular and molecular responses to ethanol

      • I. Diamond, A. S. Gordon
      Pages 175-183

    8. Helicobacter pylori alcohol dehydrogenase

      • M. Salaspuro
      Pages 185-195
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Keywords

About this book

The 39 chapters in this volume consider subjects ranging from genetics, markers, and molecular biology of alcoholism, to clinical observations and treatment. The aim is to integrate pertinent information from the fields of molecular and cell biology with view to establishing a molecular basis of alcohol use and abuse. An initial preview summarizes historical aspects of alcohol use, and subsequent chapters concern novel drugs, pharmacological aspects, gene structures, cloning, and enzymatic properties. Also contributions by "non-traditional" alcohol scientists have been included in this collection, in order to highlight possible interaction and parallels between different fields. Novel results of particular interest include up-dated summaries on receptors, enzymes, and other proteins, as well as corresponding gene structures and regulation, setting the basis for distinguishing markers and pinpointing further possible pharmacological treatments.

Editors and Affiliations

  • Department of Psychiatry, Karolinska Institutet, Huddinge University Hospital, Huddinge, Sweden

    B. Jansson

  • Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

    H. Jörnvall

  • Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden

    U. Rydberg, L. Terenius

  • Center for Biochemical and Biophysical Sciences and Medicine, Harvard Medical School, Boston, USA

    B. L. Vallee

Bibliographic Information

  • Book Title: Toward a Molecular Basis of Alcohol Use and Abuse

  • Editors: B. Jansson, H. Jörnvall, U. Rydberg, L. Terenius, B. L. Vallee

  • Series Title: Experientia Supplementum

  • DOI: https://doi.org/10.1007/978-3-0348-7330-7

  • Publisher: Birkhäuser Basel

  • eBook Packages: Springer Book Archive

  • Copyright Information: Birkhäuser Verlag 1994

  • Softcover ISBN: 978-3-0348-7332-1Published: 16 March 2012

  • eBook ISBN: 978-3-0348-7330-7Published: 13 March 2013

  • Series ISSN: 1664-431X

  • Series E-ISSN: 2504-3692

  • Edition Number: 1

  • Number of Pages: 407

  • Topics: Cell Biology, Biochemistry, general, Pharmacology/Toxicology, Psychotherapy

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