Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des Recherches Pharmaceutiques

1. Front Matter

   Pages 1-7

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2. Neuropeptides as native immune modulators

   • Vijendra K. Singh

   Pages 9-31

3. Calmodulin: Effects of cell stimuli and drugs on cellular activation

   • Margaret E. Gnegy

   Pages 33-65

4. Recent advances in benzodiazepine receptor (BZR) binding studies

   • S. P. Gupta

   Pages 67-106

5. The medicinal chemistry and therapeutic potentials of ligands of the histamine H3 receptor

   • R. Leurs, R. C. Vollinga, H. Timmerman

   Pages 107-165

6. Serotonin uptake inhibitors: Uses in clinical therapy and in laboratory research

   • Ray W. Fuller

   Pages 167-204

7. Generation of new-lead structures in computer-aided drug design

   • Nissim Claude Cohen, Vincenzo Tschinke

   Pages 205-243

8. Natriuretic hormones II

   • Elaine J. Benaksas, E. David Murray Jr., William J. Wechter

   Pages 245-288

9. Recent developments in the chemotherapy of osteoporosis

   • Indra Dwivedy, Suprabhat Ray

   Pages 289-338

10. Back Matter

    Pages 339-388

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Volume 45 of "Progress in Drug Research" contains eight reviews and the various indexes which facilitate its use and establish the connection with the previous volumes. The articles in this volume deal with neuro­ peptides as native immune modulators, with Calmodulin and with effects of cell stimuli and drugs on cellular activation, with recent advances in benzodiazepine receptor binding studies, with the medicinal chemistry and therapeutic potentials of ligands of the histamine H3 receptor, with Serotonin uptake inhibitors, with computer-aided drug design, with natri­ uretic hormones and with the recent developments in the chemotherapy of osteoporosis. In the 36 years that PDR has existed, the Editor has enjoyed the valu­ able help and advice of many colleagues. Readers, the authors of the reviews and, last but not least, the reviewers have all contributed greatly to the success of this series. Although the comments received so far have generally been favorable, it is nevertheless necessary to analyze and to reassess the current position and the future direction of such a series of monographs. So far, it has been the Editor's intention to help disseminate information on the vast domain of drug research, and to provide the reader with a tool with which to keep abreast of the latest developments and trends. The reviews in PDR are useful to the nonspecialist, who can obtain an overview of a particular field of drug research in a relatively short time.

• Arzneimittel
• chemistry
• chemotherapy
• drug
• drug discovery
• drug research
• medicinal chemistry
• peptides
• research
• serotonin

• Basel, Switzerland

  E. Jucker

• Ettingen, Switzerland

  E. Jucker

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