Overview
- Presents the most advanced knowledge in the field.
- Written by renowned experts.
- Richly illustrated.
- Includes supplementary material: sn.pub/extras
Part of the book series: Progress in Inflammation Research (PIR)
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Table of contents (13 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Proteases are everywhere from prokaryotes to eukaryotes, from virus to bacteria and in all human tissues, playing a role in many biological functions. Among these functions, the inflammatory reaction is of particular interest. In inflamed tissues, proteases can have a microbial and/or host origin and are involved not only in tissue remodeling, but also in specific signaling to resident or inflammatory cells, thereby contributing to the innate immune response.
This volume presents all advances in our knowledge of the role proteases and their inhibitors play in various diseases associated with inflammatory response. Mechanisms involved in protease signaling to cells are presented, and the different types of proteases that are present at inflammatory sites and their effects on the course of inflammation are discussed. Finally, the evidence for considering proteases and their receptors as potential molecular targets for therapeutic interventions in the treatment of inflammatory diseases is discussed in the context of specific organ inflammatory pathologies (the lung, gastrointestinal tract, skin, joints, etc.).
Editors and Affiliations
Bibliographic Information
Book Title: Proteases and Their Receptors in Inflammation
Editors: Nathalie Vergnolle, Michel Chignard
Series Title: Progress in Inflammation Research
DOI: https://doi.org/10.1007/978-3-0348-0157-7
Publisher: Springer Basel
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Basel AG 2011
Hardcover ISBN: 978-3-0348-0156-0Published: 03 August 2011
Softcover ISBN: 978-3-0348-0342-7Published: 26 November 2013
eBook ISBN: 978-3-0348-0157-7Published: 03 August 2011
Series ISSN: 1422-7746
Series E-ISSN: 2296-4525
Edition Number: 1
Number of Pages: XIV, 310
Topics: Immunology, Cell Biology, Infectious Diseases