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Physical Microbiology

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  • © 2020

Overview

  • Represents the trend in microbiology to bring together physics and biology
  • Brings down borders between the fields of microbiology and physics
  • Written by the leading experts on the microbiology of infection
  • Is a unique and multidisciplinary approach to our understanding of the relationship between bacterial biology and infection

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1267)

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Table of contents (7 chapters)

Keywords

About this book

This book emerges from the idea that specific physics-inspired approaches are necessary to understand different stage of bacterial physiology and the infections they cause. Many aspects of bacterial life depend on processes typically described by physical laws: The rheology of biofilms is determined by complex cohesive forces. Physical laws of diffusion are essential to all processes of bacterial metabolism. The formation of the numerous bacterial biomacromolecules require complex self-organization processes and their function are powered by potent molecular motors. Host-pathogen interactions during infection frequently occur in environments determined by fluid mechanics.

In this book, different chapters represent research at the interface between microbiology and physics. Topics range from intracellular organization to cell-cell interactions. A good part of the book is devoted to mechanical forces, which are involved in the function of elaborate bacterial nanomachines, chromosome segregation, and cell division. The effect of bacterial toxins provides an example of the alteration of cellular membrane properties by bacteria. Symmetrically, histones from mammalian cells alter bacterial membranes as a defense mechanism during infection.

The editors of this book, Guillaume Duménil and Sven van Teeffelen, have selected researchers at the forefront of research in physical microbiology to provide the most recent view in this fast-moving field.

The contents of this book are designed to be accessible for scientists with training in biology and for scientists with training in physics. The objective is to provide a fresh perspective on microbiology and infection by highlighting recent multidisciplinary research and favor rapid advances at this fruitful interface.

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Editors and Affiliations

  • Pathogenesis of Vascular Infections, Institut Pasteur, Paris, France

    Guillaume Duménil

  • Microbial Morphogenesis and Growth, Institut Pasteur, Paris, France

    Sven van Teeffelen

About the editors

 

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