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Antifreeze Proteins Volume 1

Environment, Systematics and Evolution

  • Book
  • © 2020

Overview

  • Informs about the evolution and systematics of antifreeze proteins

  • provides insight into the physical proprieties of AFPs

  • Presents together with Vol.2 the most comprehensive work on AFPs in general

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Table of contents (9 chapters)

  1. Ice Formation

  2. The Biology of Antifreeze Proteins

Keywords

About this book

This first volume provides a comprehensive overview on evolutionary, environmental and systematic aspects of antifreeze proteins. It shortly explains the physical properties of ice and further intelligibly describes the biology of the antifreeze proteins in different organisms, and offers a detailed insight into their history of evolution. In addition the book discusses the status of the current knowledge and ongoing research and highlights also those parts, where further investigation needs to be done. Together with the second volume on the biochemistry and molecular biology of antifreeze proteins, this book represents a unique, comprehensive work and a must-have for students and scientists in biochemistry, evolution, physiology and physical chemistry.






Editors and Affiliations

  • Department of Natural Sciences, Roskilde University, Roskilde, Denmark

    Hans Ramløv

  • Copenhagen, Denmark

    Dennis Steven Friis

About the editors

Dr. Hans Ramløv is professor of Comparative Animal Physiology at Roskilde University, Denmark. For the last 35 years he has investigated physiological adaptations to extreme environments in ectothermic animals with special emphasis on cold and drought. The research includes investigations on cryptobiosis in tardigrades, freeze tolerance in insects and vertebrates and since the early 1990’es various aspects of the properties of antifreeze proteins. Together with researchers from Norway and Denmark he has determined the structure of antifreeze proteins from the bark beetles Rhagium inquisitor and Rhagium mordax as well as the cloning and expression of these proteins into Escherichia coli. Via international collaboration this research has led to a suggested model for the molecular interaction of the R. mordax antifreeze protein with ice.Hans Ramløv has worked in extreme environments across the globe, from the Sahara via alpine areas in Europe and New Zealand to the Antarctic, Greenland and the north polar basin.

Dr. Dennis Steven Friis has a PhD within the field of protein chemistry, and is currently working in the pharmaceutical industry in Copenhagen. He has done both his masters and PhD on antifreeze protein research in collaboration with Hans Ramløv. The master’s thesis focused on cryopreservation of kidney cells in suspension, investigating the Rhagium mordax antifreeze proteins’ potential as a cryoprotective agent as well as freeze injuries in general. During the PhD he worked firstly on developing an efficient method to express, extract and purify recombinant antifreeze proteins using E. coli as the host organism. Hereafter, he investigated the physicochemical properties of the antifreeze protein, as well as creating various mutants of the protein and examining their effects on the hysteresis activity.After six years in collaboration with Hans Ramløv on the research on antifreeze proteins, he switched his career into the pharmaceutical industry, however, not before seizing the opportunity of being co-editor this book on the fascinating topic of antifreeze proteins.

Bibliographic Information

  • Book Title: Antifreeze Proteins Volume 1

  • Book Subtitle: Environment, Systematics and Evolution

  • Editors: Hans Ramløv, Dennis Steven Friis

  • DOI: https://doi.org/10.1007/978-3-030-41929-5

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-41928-8Published: 01 July 2020

  • Softcover ISBN: 978-3-030-41931-8Published: 01 July 2021

  • eBook ISBN: 978-3-030-41929-5Published: 30 June 2020

  • Edition Number: 1

  • Number of Pages: XIV, 313

  • Number of Illustrations: 5 b/w illustrations, 28 illustrations in colour

  • Topics: Protein Science, Evolutionary Biology, Biological and Medical Physics, Biophysics

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