Diagnostic Pathology of Hematopoietic Disorders of Spleen and Liver

1. Front Matter

   Pages i-xii

   PDF

2. Anatomy and Histology of Normal Liver and Spleen

   • Lynh Nguyen, Ling Zhang

   Pages 1-9

3. Diagnostic Approaches to Hematopoietic Disorders of the Spleen and Liver

   • Ling Zhang, Pukhraz Basra, Serhan Alkan

   Pages 11-35

4. Molecular and Genetic Diagnostic Approaches of Hematopoietic Disorders of the Spleen and Liver

   • Jinming Song, Rohit Sharma, Mohammad Hussaini

   Pages 37-67

5. Hairy Cell Leukemia, Hairy Cell Leukemia Variant, and Splenic Diffuse Red Pulp Small B-Cell Lymphoma

   • Wei Chen, Qin Huang

   Pages 69-82

6. Splenic Marginal Zone Lymphoma and Other Small B-Cell Lymphomas

   • Haipeng Shao

   Pages 83-109

7. Large B-Cell Lymphomas of the Spleen

   • Madhu P. Menon, Min Shi, Karthik Ganapathi

   Pages 111-142

8. Primary Hepatic B-Cell Lymphomas

   • Xin Qing, Changjun Yue

   Pages 143-152

9. Plasma Cell Neoplasms and Amyloidosis in the Liver and Spleen

   • Pei Lin

   Pages 153-163

10. Hepatosplenic T-Cell Lymphoma

    • Michelle Don, Serhan Alkan

    Pages 165-170

11. T-Cell Large Granular Lymphocytic Leukemia Involving the Liver and Spleen

    • Ling Zhang, Lugen Chen, Serhan Alkan

    Pages 171-184

12. Uncommon Mature T-Cell Lymphomas

    • Mariko Yabe, Ahmet Dogan

    Pages 185-198

13. Hodgkin Lymphoma in the Liver and Spleen

    • Joo Young Song, Saba Fatima Ali

    Pages 199-208

14. B-Lymphoblastic Leukemia/Lymphoma Involving the Spleen or Liver

    • David C. Gajzer, Lugen Chen, Ling Zhang

    Pages 209-218

15. T-Lymphoblastic Leukemia/Lymphoma Involving the Spleen or Liver

    • David C. Gajzer, Ling Zhang

    Pages 219-229

16. Aggressive Natural Killer-Cell Leukemia and T-Cell Prolymphocytic Leukemia: Two Rare and Highly Aggressive Hematologic Neoplasms Typically Involving the Liver and Spleen

    • David C. Gajzer, Ling Zhang

    Pages 231-241

17. Myeloid Neoplasms in the Liver and Spleen

    • Elizabeth Margolskee, Attilio Orazi

    Pages 243-261

18. Histiocytic and Dendritic Cell Disorders in the Liver and Spleen

    • Nukhet Tuzuner

    Pages 263-288

19. Transplant-Related Disorders in the Liver and Spleen

    • Brent K. Larson, Maha Guindi

    Pages 289-314

20. Benign Red Blood Cell Disorders in the Liver and Spleen

    • Xiaohui Zhang

    Pages 315-327

This book provides a comprehensive and up-to-date overview of the pathologic features of common benign and malignant hematopoietic disorders in spleen and liver for practicing pathologists, hematopathologists and clinicians. The authors are from large academic centers, affiliated teaching hospitals and central referral clinics and are experienced in the diagnosis of hematopoietic disorders in the spleen and liver. The book consists of 21 chapters, with the first three chapters devoted to normal histologic features, conventional, cytogenetic and molecular studies necessary for the diagnosis of hematopoietic disorders in the spleen and liver. Chapters 4 to 17 cover the primary and secondary mature B- and T/NK cell lymphomas, Hodgkin lymphoma, B and T cell lymphoblastic leukemias, myeloid neoplasms, histiocytic and dendritic neoplasms, and post-transplant disorders including post transplant lymphoproliferative disorders. Chapters 19 to 21 encompass red blood cell disorders, other benign hematologic disorders and infectious/inflammatory disorders that could mimic hematopoietic neoplasms. These chapters are formatted on specific hematopoietic neoplasms to comprise epidemiology, etiology, pathogenesis, morphology, immunophenotyping, molecular genetics, prognosis and brief treatment guidelines. Diagnostic caveats are included in order to have a quick review of the key points in each chapter.

Diagnostic Pathology of Hematopoietic Disorders of Spleen and Liver covers most, if not all of the benign and malignant hematopoietic disorders in the spleen and liver and serves as a practical and useful resource for general pathologists and hematopathologists.

• Splenectomy
• Molecular mutational analysis
• B cell lymphomas
• Hairy cell leukemia
• amyloidosis
• Hodgkin lymphoma

• Department of Pathology, Moffitt Cancer Center, Tampa, USA

  Ling Zhang, Haipeng Shao

• Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, USA

  Serhan Alkan

Ling Zhang
H. Lee Moffitt Cancer Center
Department of Hematopathology and Laboratory Medicine
Tampa, FL
USA


Haipeng Shao
H. Lee Moffitt Cancer Center
Department of Hematopathology and Laboratory Medicine
Tampa, FL 
USA


Serhan Alkan
Cedars Sinai Medical Center
Los Angeles, CA
USA

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