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Tumor Microenvironment

The Role of Chemokines – Part A

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  • © 2020

Overview

Editors:
  1. Alexander Birbrair

    1. Department of Radiology, Columbia University Medical Center, New York, USA

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  • Provides a comprehensive overview of the state-of-the-art research on the role of chemokines in the tumor microenvironment
  • Discusses the potential of targeting chemokine pathways for the treatment of cancer
  • Describes how Chemokines affect cancer immunity and tumorigenesis

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1231)

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-xi
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  2. CX3CL1 Signaling in the Tumor Microenvironment

    • Melissa J. Conroy, Joanne Lysaght
    Pages 1-12

  3. CCL3 Signaling in the Tumor Microenvironment

    • Ioannis Ntanasis-Stathopoulos, Despoina Fotiou, Evangelos Terpos
    Pages 13-21

  4. CCL4 Signaling in the Tumor Microenvironment

    • Naofumi Mukaida, So-ichiro Sasaki, Tomohisa Baba
    Pages 23-32

  5. CCL7 Signaling in the Tumor Microenvironment

    • Yeo Song Lee, Yong Beom Cho
    Pages 33-43

  6. The Multifaceted Roles of CXCL9 Within the Tumor Microenvironment

    • Shi Yong Neo, Andreas Lundqvist
    Pages 45-51

  7. CCL20 Signaling in the Tumor Microenvironment

    • Weilong Chen, Yuanyuan Qin, Suling Liu
    Pages 53-65

  8. CCL21 Programs Immune Activity in Tumor Microenvironment

    • Sherven Sharma, Pournima Kadam, Steven Dubinett
    Pages 67-78

  9. CCL22 Signaling in the Tumor Environment

    • Natascha Röhrle, Max M. L. Knott, David Anz
    Pages 79-96

  10. Back Matter

    Pages 97-101
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Keywords

About this book

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of chemokines in the tumor microenvironment. Each chapter focuses on the chemokines patterns of expression, their regulation, and their roles in immune cell recruitment, as well as how they affect cancer immunity and tumorigenesis.

Taken alongside its companion volumes, Tumor Microenvironment: The Role of Chemokines – Part A updates us on what we know about various aspects of the tumor microenvironment as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking a comprehensive update on research in the tumor microenvironment.

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Editors and Affiliations

  • Department of Radiology, Columbia University Medical Center, New York, USA

    Alexander Birbrair

About the editor

Alexander Birbrair received his Bachelor’s Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA).

Bibliographic Information

  • Book Title: Tumor Microenvironment

  • Book Subtitle: The Role of Chemokines – Part A

  • Editors: Alexander Birbrair

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-030-36667-4

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-36666-7Published: 15 February 2020

  • Softcover ISBN: 978-3-030-36669-8Published: 15 February 2021

  • eBook ISBN: 978-3-030-36667-4Published: 14 February 2020

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XI, 101

  • Number of Illustrations: 2 b/w illustrations, 13 illustrations in colour

  • Topics: Cell Biology, Cancer Research, Oncology

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