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Tumor Microenvironment

Hematopoietic Cells – Part A

  • Provides a comprehensive overview of the state-of-the-art research on the role of hematopoietic components in tumor development and progression
  • Discusses the role of neutrophils, basophils, T helper cells, cytotoxic lymphocytes, fibrocytes, and myeloid-derived suppressor cells, and more in the tumor microenvironment
  • Illustrates the functional interaction of hematopoietic cells with tumor cells

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1224)

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-xi
  2. Neutrophils in the Tumor Microenvironment

    • Lingyun Wu, Sugandha Saxena, Rakesh K. Singh
    Pages 1-20
  3. Basophils in Tumor Microenvironment and Surroundings

    • Giancarlo Marone, Adriana Rosa Gambardella, Fabrizio Mattei, Jacopo Mancini, Giovanna Schiavoni, Gilda Varricchi
    Pages 21-34
  4. Janus or Hydra: The Many Faces of T Helper Cells in the Human Tumour Microenvironment

    • Florian Guisier, Mateus Camargo Barros-Filho, Leigha D. Rock, Megan Strachan-Whaley, Erin A. Marshall, Graham Dellaire et al.
    Pages 35-51
  5. Mucosal-Associated Invariant T Cells in Tumors of Epithelial Origin

    • Nicholas A. Zumwalde, Jenny E. Gumperz
    Pages 63-77
  6. Fibrocytes in the Tumor Microenvironment

    • David Roife, Jason B. Fleming, Richard H. Gomer
    Pages 79-85
  7. Models for Monocytic Cells in the Tumor Microenvironment

    • Sharon W. L. Lee, Giulia Adriani, Roger D. Kamm, Mark R. Gillrie
    Pages 87-115
  8. Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

    • Matthew Dysthe, Robin Parihar
    Pages 117-140
  9. Back Matter

    Pages 141-146

About this book

Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components of the tumor microenvironment. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include neutrophils, basophils, T helper cells, cytotoxic lymphocytes, fibrocytes, and myeloid-derived suppressor cells, and more.

Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Hematopoietic Cells – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Editors and Affiliations

  • Columbia University Medical Center, Department of Radiology, New York, NY, USA, Federal University of Minas Gerais, Department of Pathology, Belo Horizonte, Brazil

    Alexander Birbrair

About the editor

Alexander Birbrair received his Bachelor’s Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA).

Bibliographic Information

  • Book Title: Tumor Microenvironment

  • Book Subtitle: Hematopoietic Cells – Part A

  • Editors: Alexander Birbrair

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-030-35723-8

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-35722-1Published: 09 February 2020

  • Softcover ISBN: 978-3-030-35725-2Published: 09 February 2021

  • eBook ISBN: 978-3-030-35723-8Published: 08 February 2020

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XI, 146

  • Number of Illustrations: 2 b/w illustrations, 17 illustrations in colour

  • Topics: Cell Biology, Cancer Research, Oncology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access