Overview
- Nominated as an outstanding PhD thesis by the Australian Institute for Bioengineering and Nanotechnology
- Describes the design of various novel nano-strategies for prostate cancer detection
- Offers an extensive investigation into the use of next-generation urinary biomarkers
- Includes data on clinical evaluation to progress clinical translation
Part of the book series: Springer Theses (Springer Theses)
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Table of contents (7 chapters)
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Front Matter
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Back Matter
Keywords
- Prostate Cancer Detection
- Precision Medicine
- Urinary Nanodiagnostics
- Clinical Translation
- Biosensor Development
- Next-generation Prostate Cancer Biomarkers
- Non-invasive Prostate Cancer Nanodiagnostics
- TMPRSS2–ETS Fusion Genes
- Electro Chemistry
- Surface-enhanced Raman spectroscopy
- Enhanced Detection Performance
- Nanodiagnostics for Clinical Applications
- Lab-in-a-drop
- Fluidic Mixing
About this book
This book presents a unique concept of merging nanotechnology and novel urinary biomarkers for accurate early prostate cancer detection, discussing an entire progressive pipeline of innovative new strategies in biosensor development, from a simple colorimetric system to a complex system for simultaneous multiple biomarker sensing. For newcomers to the field of nucleic acid biosensing, it also describes various isothermal amplification and amplification-free strategies, which are currently the main research areas. Lastly, the book introduces and demonstrates the notion of clinical nanobiosensor validation toward clinical translation: the ultimate aim of researchers in the biosensor field. This book is a valuable reference resource learners seeking inspiration for cancer biosensor development.
Authors and Affiliations
Bibliographic Information
Book Title: Advancing Gene Fusion Detection Towards Personalized Cancer Nanodiagnostics
Authors: Kevin M. Koo
Series Title: Springer Theses
DOI: https://doi.org/10.1007/978-3-030-31000-4
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2019
Hardcover ISBN: 978-3-030-30999-2Published: 07 October 2019
Softcover ISBN: 978-3-030-31002-8Published: 07 October 2020
eBook ISBN: 978-3-030-31000-4Published: 24 September 2019
Series ISSN: 2190-5053
Series E-ISSN: 2190-5061
Edition Number: 1
Number of Pages: XIII, 102
Topics: Biomedical Engineering/Biotechnology, Nanotechnology, Biomedical Engineering and Bioengineering, Cancer Research