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Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors

  • Book
  • © 2019

Overview

Editors:
  1. Dustin L. Williams

    1. Department of Veterans Affairs, Department of Orthopaedics, Department of Pathology, Department of Bioengineering, Department of Physical Medicine and Rehabilitation, University of Utah; Uniformed Services University of the Health Sciences, Salt Lake City, Bethesda, USA

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  • Outlines the benefits of targeting biofilm-related infections
  • Provides discussion on creating more effective antimicrobial coatings for medical implants
  • Offers perspective on regulatory management for clinical and industrial environments

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-xvii
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  2. We Begin to Target the Biofilm

    • Dustin L. Williams
    Pages 1-10

  3. Biofilm Infections in Orthopedic Surgery and Their Impact on Commercial Product Development

    • David A. Armbruster
    Pages 11-27

  4. Catheter-Associated Urinary Tract Infections: Development of a Test Method for Assessing the Efficacy of Antimicrobial Technologies/Products

    • Jennifer Summers, Darla M. Goeres
    Pages 29-53

  5. Biofilms and Wound Infection Research in the US Military

    • Kevin S. Akers, Joseph C. Wenke, Clinton K. Murray
    Pages 55-69

  6. Targeting Biofilms in Orthopedic Infection

    • Karan Goswami, Javad Parvizi
    Pages 71-83

  7. Translation of Antibiofilm Technologies to Wounds and Other Clinical Care

    • Matthew Myntti
    Pages 85-95

  8. Central Venous Catheters and Biofilm Infections

    • Bryan Haymond
    Pages 97-105

  9. A Biofilm-Based Approach to the Diagnosis and Management of Postoperative Spine Infection

    • Jeremy D. Shaw
    Pages 107-130

  10. Targeting Biofilms in Translational Research

    • Nicholas N. Ashton, Dustin L. Williams
    Pages 131-155

  11. Back Matter

    Pages 157-162
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Keywords

About this book

This book offers a much-needed discussion on the targeting of biofilm-related infections. Chapters include discussions on the impact of biofilm on medical implants, industrial applications, as well as wound and tissue infections. It also offers discussions on regulatory management for industrial sectors and medical environments. Given that there continues to be a paucity of effective antimicrobial products, devices, and coatings in clinical and industrial use that effectively reduce rates of infection or biofilm-related problems, Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors, offers a fresh and much-needed perspective aimed at helping create healthier controlled environments and safer devices.  


This comprehensive book is indispensable for industrial and academic translational researchers, device developers, and regulatory experts looking to create more effective antimicrobial products. 

Editors and Affiliations

  • Department of Veterans Affairs, Department of Orthopaedics, Department of Pathology, Department of Bioengineering, Department of Physical Medicine and Rehabilitation, University of Utah; Uniformed Services University of the Health Sciences, Salt Lake City, Bethesda, USA

    Dustin L. Williams

About the editor

Dustin L. Williams has developed translational animal models of biofilm-related infection to mimic clinical scenarios, such as open fractures, wherein biofilms from natural sources (e.g. soil) may be initial contaminants of a wound site. He is a founding member of three companies that have been launched out of the University of Utah; each focusing on anti-biofilm technologies. In 2016, he became the Director of the Bone and Joint Research Lab located in the Department of Veterans Affairs in Salt Lake City, UT. Dustin and his team manage research programs that span biofilm-related infections, osseointegration, bone pathologies such as heterotopic ossification, and specialize in hard plastic embedment for histological analysis.

 

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