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Endometrial Gene Expression

An Emerging Paradigm for Reproductive Disorders

Editors:

  • Presents the state of the art in endometrial gene expression as well as recent developmental findings relating to reproduction and reproductive disorders

  • Discusses gene expression in cases of repeated implant failure, immune profiling, recurrent pregnancy loss, infection, uterine fibroids, endometriosis and other reproductive and gynecological malignancies

  • Ideal for for reproductive endocrinologists, gynecologists, fetal medicine specialists, and all clinicians treating female infertility

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Softcover Book USD 99.99
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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xiii
  2. Endometrial Development and Its Fine Structure

    • Takeshi Kurita, Jumpei Terakawa
    Pages 1-32
  3. T Cell-Related Endometrial Gene Expression in Normal and Complicated Pregnancies

    • Li Wu, Aihua Liao, Alice Gilman-Sachs, Joanne Kwak-Kim
    Pages 51-66
  4. Role of Immunoregulatory Cytokine IL-15 in the Endometrium

    • Svetlana Dambaeva, Kenneth D. Beaman
    Pages 67-74
  5. Endometrial Receptivity by Endometrial Receptivity Analysis (ERA) for Infertility

    • Maria Ruiz-Alonso, Jose Miravet-Valenciano, Pilar López, Carlos Simón
    Pages 91-102
  6. Endometrium Gene Expression and Epigenetic Regulation in Reproductive Failure

    • Jin Huang, Ruizhe Zhang, Chi Chiu Wang, Tin Chiu Li
    Pages 103-116
  7. Endometrial Gene Expression for HHV-6

    • Carolyn Coulam
    Pages 117-124
  8. Endometrial Immune-Inflammatory Gene Signatures in Endometriosis

    • Jessica E. Miller, Lindsey K. Symons, Ryan M. Marks, Chandrakant Tayade
    Pages 141-158
  9. Gene Expression in Endometriosis

    • Niraj Joshi, Ren-Wei Su, Asgerally Fazleabas
    Pages 159-180
  10. MicroRNA and Endometriosis

    • Swati Agrawal, Christian M. Becker
    Pages 181-197
  11. Metabolic and Nutritional Impact on Endometrial Gene Expression and Reproductive Disorder

    • Lianghui Diao, Songchen Cai, Jinli Ding, Yong Zeng
    Pages 199-214
  12. Back Matter

    Pages 215-220

About this book

The endometrium goes through cyclical changes under the influence of hormones, and immune effectors in the endometrium change their populations cyclically as well. Dynamic changes in immune effectors determine endometrial cytokine and chemokine milieus and, consequently, the endometrial immune response. Endometrial immune responses have been shown to be important for trophoblast invasion and early pregnancy. Indeed, dysregulated endometrial inflammatory immune responses are associated with reproductive failures, such as recurrent pregnancy losses, repeated implantation failure, and gynecological diseases with oncogenic potential. Hence, the investigation of endometrial gene expression may predict infertility, gynecological and oncological conditions. 


This book presents the state of the art in endometrial gene expression as well as recent developmental findings relating to reproduction and reproductive disorders. It begins with a review of the genetic regulation of urogenital tract formation and molecular mechanism underlying the physiology of menstrual cycle before moving on to the current and emerging technological advances in molecular biology. Endometrial gene expressions of immune inflammatory conditions, viral infection, metabolic and nutritional conditions, and reproductive disorders are then presented in following chapters. Examples of the use and interpretation of gene expression in clinical scenarios including recurrent pregnancy losses,  infertility and multiple implantation failures are presented with currently available endometrial gene analysis.

Utilizing the latest evidence and clinical guidelines, Endometrial Gene Expression will be a cutting-edge resource for gynecologist, reproductive immunologist, reproductive endocrinologists, obstetrician, maternal fetal medicine specialist and other health care providers in the field of reproductive medicine.  

Editors and Affiliations

  • Reproductive Medicine and Immunology Clinical Sciences, Obstetrics and Gynecology, Microbiology and Immunology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, Vernon Hills, USA

    Joanne Kwak-Kim

About the editor

Joanne Kwak-Kim, MD, MPH, Department of Obstetrics and Gynecology, Department of Microbiology and Immunology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, Vernon Hills, IL, USA.

 

Bibliographic Information

  • Book Title: Endometrial Gene Expression

  • Book Subtitle: An Emerging Paradigm for Reproductive Disorders

  • Editors: Joanne Kwak-Kim

  • DOI: https://doi.org/10.1007/978-3-030-28584-5

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-28583-8Published: 21 November 2019

  • Softcover ISBN: 978-3-030-28586-9Published: 21 November 2020

  • eBook ISBN: 978-3-030-28584-5Published: 08 November 2019

  • Edition Number: 1

  • Number of Pages: XIII, 220

  • Number of Illustrations: 15 illustrations in colour

  • Topics: Reproductive Medicine, Gynecology, Gene Expression

Buy it now

Buying options

eBook USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 129.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access