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Mastocytosis

A Comprehensive Guide

  • Book
  • © 2020

Overview

Editors:
  1. Cem Akin

    1. Professor of Medicine, Division of Allergy and Clinical Immunology, University of Michigan, Ann Arbor, USA

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  • Features treatment guidance incorporating newly approved drugs, providing best practices on how to approach treatment and management of mastocytosis
  • Written by internationally renowned clinicians, allowing it to function as an indispensable, multi-disciplinary resource for medical professionals around the world
  • A highly relevant topic in allergy medicine, this book offers an in-depth guide to diagnosis and management of mastocytosis, an often underdiagnosed disease.

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xii
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  2. Overview of Mast Cells in Human Biology

    • Dean D. Metcalfe, Do-Kyun Kim, Ana Olivera
    Pages 1-22

  3. Mastocytosis: Overview of Diagnosis and Classification

    • Cem Akin, Sigurd Broesby-Olsen, Peter Valent
    Pages 23-34

  4. Clinical Approach to a Patient with Elevated Serum Tryptase: Implications of Acute Versus Basally Elevated Levels

    • Jonathan J. Lyons, Lawrence B. Schwartz
    Pages 35-54

  5. Urinary Markers of Mast Cell Disease and Their Role in Diagnosis and Management

    • Joseph H. Butterfield, Thanai Pongdee, Anupama Ravi
    Pages 55-67

  6. Skin Disease in Mastocytosis

    • Zita-Rose Manjaly Thomas, Karin Hartmann
    Pages 69-91

  7. Pediatric Mastocytosis

    • Iván Alvarez-Twose, Melody C. Carter
    Pages 93-114

  8. Gastrointestinal Manifestations of Systemic Mastocytosis

    • Matthew J. Hamilton
    Pages 115-122

  9. Systemic Mastocytosis and Bone-Related Events

    • Kamyar Asadipooya, Loren Wissner Greene
    Pages 123-140

  10. Anaphylaxis in Mastocytosis

    • Theo Gülen, Joanne N. G. Oude Elberink, Knut Brockow
    Pages 141-155

  11. Venom Allergy and Management in Mastocytosis

    • Patrizia Bonadonna, Roberta Zanotti
    Pages 157-174

  12. Drug Allergy and Perioperative Management of Mastocytosis

    • Mariana Castells
    Pages 175-186

  13. Mastocytosis in Pregnancy

    • Dawn Lei, Anna Kovalszki
    Pages 187-205

  14. KIT and Other Mutations in Mastocytosis

    • Siham Bibi, Michel Arock
    Pages 207-230

  15. Management of Hematologic Disease in Mastocytosis

    • Hyun Don Yun, Celalettin Ustun
    Pages 231-255

  16. Tyrosine Kinase Inhibitors in Systemic Mastocytosis

    • Mohamad Jawhar, Jason Gotlib, Andreas Reiter
    Pages 257-265

  17. International Support and Advocacy for Mast Cell Disease Patients and Caregivers

    • Susan V. Jennings, Valerie M. Slee, Jessica S. Hobart, Lisa Morrison Thuler, David W. Mayne, Mercedes Martín-Martínez et al.
    Pages 267-286

  18. History and Current Status of Mastocytosis Research in the European Competence Network on Mastocytosis

    • Peter Valent, Michel Arock, Emir Hadzijusufovic, Wolfgang R. Sperr, Karin Hartmann, Cem Akin et al.
    Pages 287-299

  19. Back Matter

    Pages 301-307
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Keywords

About this book

This unique book offers an in-depth, best-practices guide to diagnosis and management of mastocytosis, a too-often underdiagnosed disease.


Mastocytosis: A Comprehensive Guide will open with a general overview and discussion of mast cell biology, addressing tryptase and other diagnostic markers in detail. Comprehensive diagnostic criteria and classification will follow, with special emphasis on commonly-seen related manifestations:  skin disease, pediatric mastocytosis, gastrointestinal indicators, osteoporosis, anaphylaxis, venom and drug allergy, and pregnancy.  


Mastocytosis will be an ideal resource for not only the allergist confronted with this condition,  but for a growing, multi-disciplinary audience of hematologists, gastroenterologists, dermatologists, pediatricians, primary care providers and other clinicians who encounter this disease in their patients. 
 




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Editors and Affiliations

  • Professor of Medicine, Division of Allergy and Clinical Immunology, University of Michigan, Ann Arbor, USA

    Cem Akin

About the editor

Cem Akin, MD, PhD

Professor of Medicine

University of Michigan, Department of Internal Medicine

Division of Allergy and Clinical Immunology

Ann Arbor, MI 48105 

Bibliographic Information

  • Book Title: Mastocytosis

  • Book Subtitle: A Comprehensive Guide

  • Editors: Cem Akin

  • DOI: https://doi.org/10.1007/978-3-030-27820-5

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2020

  • Softcover ISBN: 978-3-030-27822-9Published: 25 December 2019

  • eBook ISBN: 978-3-030-27820-5Published: 01 December 2019

  • Edition Number: 1

  • Number of Pages: XII, 307

  • Number of Illustrations: 2 b/w illustrations, 58 illustrations in colour

  • Topics: Allergology

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