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Severe Asthma in Children and Adolescents

Mechanisms and Management

  • Thoroughly explores and considers the impact of age, special considerations in young children, issues in adherence, and the importance of a formal approach in the transition to adult care for adolescent patients with severe asthma
  • Written by experts in the field, this book focuses on multidisciplinary management of severe asthma, including information updated current research and future directions in the field
  • Addresses severe asthma in children as a heterogeneous and often difficult-to-treat disorder, thereby approaching the subject in consideration to the disproportionate amount of asthma related healthcare expenditures

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xii
  2. General Overview

    1. Front Matter

      Pages 1-1
    2. The Epidemiology of Severe Childhood Asthma

      • Adnan Custovic, Fernando D. Martinez
      Pages 3-18
    3. Special Considerations in Preschool Age

      • Maura Kere, Erik MelĂ©n
      Pages 19-46
  3. Diagnosis of Severe Asthma

    1. Front Matter

      Pages 47-47
    2. Confirming the Diagnosis of Severe Asthma in Children

      • Andrew Bush, Samatha Sonnappa
      Pages 49-71
    3. Asthma Plus: Comorbidities in Severe Childhood Asthma

      • Marina Martinez-Garri, Jonathan M. Gaffin
      Pages 73-93
  4. Management of Severe Asthma

    1. Front Matter

      Pages 95-95
    2. A Structured Multidisciplinary Approach to Managing Difficult-to-Treat Asthma in Children

      • Dara B. O’Donoghue, Michael D. Shields
      Pages 97-112
    3. Stepwise Pharmacological Approach to Severe Childhood Asthma

      • Ina St. Onge, Karen M. McDowell, Theresa W. Guilbert
      Pages 113-131
    4. Immunotherapy and Immunomodulators

      • Nicole Akar-Ghibril, Ahmad Salaheddine Naja, Wanda Phipatanakul
      Pages 133-155
    5. Special Considerations for the Management of Severe Preschool Wheeze

      • Katherine Rivera-Spoljaric, Leonard B. Bacharier
      Pages 157-181
    6. Management of Medication Side Effects and Complications

      • Louise Selby, Louise J. Fleming
      Pages 183-211
    7. Management of Acute, Severe, and Life-Threatening Exacerbations

      • Angela Marko, Elizabeth Pace, Kristie R. Ross
      Pages 213-235
    8. Severe Asthma During Adolescence and the Transition to Adulthood

      • Erick Forno, Sejal Saglani
      Pages 237-247
  5. Current and Future Research

    1. Front Matter

      Pages 249-249
    2. Potential Therapeutic Options for Severe Asthma in Children: Lessons from Adult Trials

      • Elissa M. Abrams, Heather E. Hoch, Allan B. Becker, Stanley J. Szefler
      Pages 287-312
    3. Genomics and Pharmacogenomics of Severe Childhood Asthma

      • Klaus Bønnelykke, Gerard H. Koppelman, Elise M. A. Slob, Susanne J. H. Vijverberg, Anke H. Maitland-van der Zee
      Pages 313-341

About this book

This book provides readers with a comprehensive review of severe asthma in children and adolescents, covering epidemiology, genetics, risk factors, co-morbidities, clinical presentation, diagnosis and treatment. Written by leaders in the field, chapter discussions draw on the mechanisms driving the disease, genetics, multidisciplinary approaches, immunomodulators, and other important aspects in the management of the disease. 

Severe Asthma in Children and Adolescents: Mechanisms and Management is designed to be a practical guide, opening with an introduction on the epidemiology of severe childhood asthma, as well as a discussion of special considerations of the disease unique to the preschool-aged patient.  The distinctions between the diagnosis and management of asthma in young children of various ages, and specific approaches for the adolescent with severe asthma, including the transition into adult care are then addressed. Finally, the book closes with a discussion on the current state and future avenues for severe asthma research. 

Severe Asthma in Children and Adolescents is an indispensable reference for the healthcare professional, for basic and translational researchers, as well as for students, residents and fellows.



Editors and Affiliations

  • Children’s Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, USA

    Erick Forno

  • Imperial College London, National Heart & Lung Institute, London, UK

    Sejal Saglani

About the editors

Erick Forno, MD, MPH

Division of Pediatric Pulmonary Medicine

Children’s Hospital of Pittsburgh; Department of Pediatrics

University of Pittsburgh School of Medicine

Pittsburgh, Pennsylvania, USA

Sejal Saglani

Paediatric Respiratory Medicine

National Heart & Lung Institute

Imperial College London

London, United Kingdom

 



Bibliographic Information

  • Book Title: Severe Asthma in Children and Adolescents

  • Book Subtitle: Mechanisms and Management

  • Editors: Erick Forno, Sejal Saglani

  • DOI: https://doi.org/10.1007/978-3-030-27431-3

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2020

  • Softcover ISBN: 978-3-030-27433-7Published: 24 December 2019

  • eBook ISBN: 978-3-030-27431-3Published: 13 November 2019

  • Edition Number: 1

  • Number of Pages: XII, 365

  • Number of Illustrations: 11 b/w illustrations, 21 illustrations in colour

  • Topics: Allergology, Pediatrics

Buy it now

Buying options

eBook USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access