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Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics

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  • © 2019

Overview

Editors:
  1. Erika Ruiz-Garcia

    1. Department of Gastrointestinal Medical Oncology & Translational Medicine Laboratory, Instituto Nacional de Cancerologia, Mexico City, Mexico

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  2. Horacio Astudillo-de la Vega

    1. Translational Research Laboratory in Cancer & Celullar Therapy, Hospital de Oncologia, Siglo XXI, IMSS, Mexico City, Mexico

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  • The book intent to address the complexity field of translational cancer research
  • Offer a comprehensive overview of the onco-omics applications in the new era of cancer personal genomics research
  • Discuses evidence-based medicine about the translational cancer research to clinicians and biomedical scientists

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1168)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-x
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  2. Pharmaco-Geno-Proteo-Metabolomics and Translational Research in Cancer

    • Edith A. Fernández-Figueroa, Saul Lino-Silva, Jorge E. Peña-Velasco, Claudia Rangel-Escareño
    Pages 1-7

  3. Next Generation Sequencing (NGS): A Revolutionary Technology in Pharmacogenomics and Personalized Medicine in Cancer

    • Stefania Morganti, Paolo Tarantino, Emanuela Ferraro, Paolo D’Amico, Bruno Achutti Duso, Giuseppe Curigliano
    Pages 9-30

  4. Pharmaco-epigenomics: On the Road of Translation Medicine

    • César López-Camarillo, Dolores Gallardo-Rincón, María Elizbeth Álvarez-Sánchez, Laurence A. Marchat
    Pages 31-42

  5. Design and Implementing Pharmacogenomics Study in Cancer

    • María Luisa Romero Lagunes, Francisco Emilio Vera Badillo
    Pages 43-77

  6. Onco-omics Approaches and Applications in Clinical Trials for Cancer Patients

    • Juan-Manuel Hernandez-Martinez, Roberto Sánchez-Reyes, J. G. De la Garza-Salazar, Oscar Arrieta
    Pages 79-90

  7. Issues and Ethical Considerations in Pharmaco-oncogenomics

    • Gilberto Morgan
    Pages 91-101

  8. Pharma-Oncogenomics in the Era of Personal Genomics: A Quick Guide to Online Resources and Tools

    • Rohan P. Joshi, David F. Steiner, Eric Q. Konnick, Carlos J. Suarez
    Pages 103-115

  9. Immuno-Oncology in the Era of Personalized Medicine

    • William R. Gwin III, Mary L. Disis, Erika Ruiz-Garcia
    Pages 117-129

  10. CAR-T cell and Personalized Medicine

    • Marlid Cruz-Ramos, Jesús García-Foncillas
    Pages 131-145

  11. Oncobiome at the Forefront of a Novel Molecular Mechanism to Understand the Microbiome and Cancer

    • H. Astudillo-de la Vega, O. Alonso-Luna, J. Ali-Pérez, C. López-Camarillo, E. Ruiz-Garcia
    Pages 147-156

  12. Nutrition, Cancer and Personalized Medicine

    • Jóse Ali Flores-Pérez, Fabiola de la Rosa Oliva, Yacab Argenes, Abelardo Meneses-Garcia
    Pages 157-168

  13. Back Matter

    Pages 169-171
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Keywords

About this book

Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. On the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient’s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and SNPs, and even more, taking into account the inmume system, the metabolism and maybe in the next future also the microbiome. 

Editors and Affiliations

  • Department of Gastrointestinal Medical Oncology & Translational Medicine Laboratory, Instituto Nacional de Cancerologia, Mexico City, Mexico

    Erika Ruiz-Garcia

  • Translational Research Laboratory in Cancer & Celullar Therapy, Hospital de Oncologia, Siglo XXI, IMSS, Mexico City, Mexico

    Horacio Astudillo-de la Vega

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