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Angiotensin-(1-7)

A Comprehensive Review

  • Book
  • © 2019

Overview

  • The first book addressing in full the most important aspects of Angiotensin-(1-7)

  • An integrative view of the modulatory biological actions of Ang-(1-7) within the renin-angiotensin system

  • Discusses the therapeutic potential of Ang-(1-7) emerging from preclinical and clinical trials

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Table of contents (15 chapters)

  1. Tools for Studying Angiotensin-(1-7)

  2. Actions of Angiotensin-(1-7)

Keywords

About this book

This is the first book addressing in full the most important aspects of the angiotensin-(1-7), the key peptide of the protective axis and the main component in the new modulatory concept of the renin-angiotensin system. It features a detailed review of angiotensin-(1-7) and its receptor Mas, comprising the historical background, enzymatic pathways for generation, functions, integrative aspects of its protective profile, and its therapeutic potential. It also encompasses a comprehensive presentation of current knowledge about its widespread biological actions on several tissues, as well as the most recent scientific achievements, emerging from preclinical and clinical trials. 


Dr. Santos is a renowned researcher on the Renin-Angiontensin system, with remarkable achievements regarding the role of peptides such as alamandine and angiontensin-(1-7). He has also worked on the potential clinical applicability of angiotensin-(1-7)-related drugs for cardiovascular diseases. He has an extensive publication record in the field, including the publication of the book The Protective Arm of the Renin Angiotensin System (Academic Press, 2015).

Angiotensin-(1-7) will make a unique contribution to the literature and will be an important resource for biomedical students and researchers, medical practitioners and any other professional interested in this peptide and its role in the renin-angiotensin system.


Editors and Affiliations

  • Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

    Robson Augusto Souza Santos

About the editor

Dr. Santos obtained his medical degree from the Medical School of Itajuba (1976), a master's degree in Biological Sciences (Physiology and Pharmacology) from the Federal University of Minas Gerais (1979) and a PhD in Physiology from the University of São Paulo (1983). He completed his postdoc at the Cleveland Clinic Foundation from 1986 to 1989. He is currently emeritus professor at the Federal University of Minas Gerais and the coordinator of INCT-NanoBiofar (National Institute for NanoBiopharmaceutics). He has experience in physiology with emphasis in cardiovascular physiology. His main works are related to the following topics: Angiotensin-(1-7), angiotensin II, hypertension, and the renin-angiotensin system. His research also includes potential clinical applicability of angiotensin-(1-7)-related drugs for cardiovascular diseases. He has an extensive publication record in the field and is co-author of the book The Protective Arm of the Renin Angiotensin System (Academic Press, 2015).


Bibliographic Information

  • Book Title: Angiotensin-(1-7)

  • Book Subtitle: A Comprehensive Review

  • Editors: Robson Augusto Souza Santos

  • DOI: https://doi.org/10.1007/978-3-030-22696-1

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-030-22695-4Published: 02 September 2019

  • Softcover ISBN: 978-3-030-22698-5Published: 02 September 2020

  • eBook ISBN: 978-3-030-22696-1Published: 21 August 2019

  • Edition Number: 1

  • Number of Pages: XIII, 240

  • Number of Illustrations: 10 b/w illustrations, 23 illustrations in colour

  • Topics: Cardiology, Human Physiology

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