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Genetic Damage in Human Spermatozoa

  • Book
  • © 2019

Overview

Editors:
  1. Elisabetta Baldi

    1. Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy

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    You can also search for this editor in PubMed   Google Scholar

  2. Monica Muratori

    1. Department of Experimental and Clinical Biomedical Sciences “Mario Serio”, University of Florence, Florence, Italy

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • The book will also discuss its relation to fertility and transgenerational heritable effects
  • The volume offers new strategies to prevent DNA damage
  • Offers a comprehensive review of all the causes of DNA damage

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1166)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Genetic Factors Affecting Sperm Chromatin Structure

    • Mélina Blanco, Julie Cocquet
    Pages 1-28

  3. Age-Dependent De Novo Mutations During Spermatogenesis and Their Consequences

    • Francesca Cioppi, Elena Casamonti, Csilla Krausz
    Pages 29-46

  4. The Sperm Epigenome: Implications for Assisted Reproductive Technologies

    • Douglas T. Carrell
    Pages 47-56

  5. Epigenetic Transgenerational Inheritance

    • Joan Blanco Rodríguez, Cristina Camprubí Sánchez
    Pages 57-74

  6. Sperm DNA Fragmentation: Mechanisms of Origin

    • Monica Muratori, Sara Marchiani, Lara Tamburrino, Elisabetta Baldi
    Pages 75-85

  7. Sperm DNA Fragmentation: Consequences for Reproduction

    • Luke Simon, Benjamin Emery, Douglas T. Carrell
    Pages 87-105

  8. Oxidative Damage to Sperm DNA: Attack and Defense

    • Joel R. Drevet, R. J. Aitken
    Pages 107-117

  9. Interventions to Prevent Sperm DNA Damage Effects on Reproduction

    • Sandro C. Esteves
    Pages 119-148

  10. Cryopreservation of Sperm: Effects on Chromatin and Strategies to Prevent Them

    • Donatella Paoli, Marianna Pelloni, Andrea Lenzi, Francesco Lombardo
    Pages 149-167

  11. Effect on Sperm DNA Quality Following Sperm Selection for ART: New Insights

    • Nicoletta Tarozzi, Marco Nadalini, Andrea Borini
    Pages 169-187

  12. Sperm DNA Damage in Cancer Patients

    • Hermance Beaud, Amelie R. Tremblay, Peter T. K. Chan, Geraldine Delbes
    Pages 189-203

  13. Back Matter

    Pages 205-210
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Keywords

About this book

There are several types of damage that can be found in the male gamete. This book covers the genetic damage in spermatozoa that can originate during spermatogenesis, or during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.

Editors and Affiliations

  • Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy

    Elisabetta Baldi

  • Department of Experimental and Clinical Biomedical Sciences “Mario Serio”, University of Florence, Florence, Italy

    Monica Muratori

About the editors

Dr. Baldi started to work in sperm biology in 1990, by studying several aspect of sperm functions as well as DNA damage. She published 155 publications in IF journals with peer review.  She has been invited as speaker in many National and International Congresses and Symposia.  She is currently associate professor of Clinical Pathology at the University of Florence and responsible of the Laboratory of semen analysis and semen cryopreservation of the Azienda Ospedaliera-Universitaria Careggi

 

Dr. Muratori started to work in sperm biology in 1997, by mainly studying sperm DNA damage. She published 80 publications with IF journals with peer review. She has been invited as speaker in many National and International Congresses and Symposia.  She is currently researcher of Applied Technical and Medical Sciences at the University of Florence

Bibliographic Information

  • Book Title: Genetic Damage in Human Spermatozoa

  • Editors: Elisabetta Baldi, Monica Muratori

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-030-21664-1

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-030-21663-4Published: 24 July 2019

  • Softcover ISBN: 978-3-030-21666-5Published: 14 August 2020

  • eBook ISBN: 978-3-030-21664-1Published: 12 July 2019

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 2

  • Number of Pages: XIII, 210

  • Number of Illustrations: 1 b/w illustrations, 9 illustrations in colour

  • Topics: Gene Expression, Gene Function, Human Physiology

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