Overview
- Fully colored mechanistic figures
- In-depth analysis of bioactive sphingolipid metabolism and function
- Detailed description of the properties of the enignamtic ceramide channel
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1159)
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Table of contents (8 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This book is about the various roles of bioactive ceramides and other sphingolipids in cellular biology. The enigmatic biophysical and biochemical properties of ceramides and their propensity to influence membranes whether as rafts or protein-permeable channels are heavily discussed. Metabolism of ceramides and their metabolites is also focused with ceramide synthase family of proteins being a target of extensive review. Ceramide 1-phosphate and other sphingolipids are also presented in cellular physiology and pathophysiology. Prokaryotic origins of mitochondria at the level of membranes and the occurrence of apoptosis in bacteria are presented.
Many aspects of ceramide and sphingolipid biology are addressed in this book. Its focus is the metabolism of ceramide in normal and diseased states and the biophysical and biochemical mechanisms governing the bioactivity of these molecules. Sphingolipid research has surged over the past thirty years and this book gathers the recent findings of various aspects of sphingolipid biochemistry.
World-renowned scientists from the field of lipid biology, specifically sphingolipid biochemistry, were gathered to write this book. Scholars from most continents of the globe committed to write diligently about their expertise and the newest findings in the relevant fields. This book came to fruition after almost a year and a half of laborious preparation and diligent writings.
This book is targeted to the experienced reader who is looking to read about the various aspects of bioactive ceramide signaling, as well as to the newcomer into the field, as the topics are explained in concise yet very informative manner. The authors and editor wish all readers a pleasant time reading this volume, and are adamant that this book will meet all expectations.
Editors and Affiliations
About the editor
Bibliographic Information
Book Title: Bioactive Ceramides in Health and Disease
Book Subtitle: Intertwined Roles of Enigmatic Lipids
Editors: Johnny Stiban
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-030-21162-2
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2019
Hardcover ISBN: 978-3-030-21161-5Published: 20 September 2019
Softcover ISBN: 978-3-030-21164-6Published: 20 September 2020
eBook ISBN: 978-3-030-21162-2Published: 09 September 2019
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XII, 153
Number of Illustrations: 17 b/w illustrations, 14 illustrations in colour
Topics: Molecular Medicine, Lipidology, Cancer Research, Biomedical Engineering/Biotechnology