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Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy

A Comprehensive Guide

  • Book
  • © 2019

Overview

Editors:
  1. Daniel M. Trifiletti

    1. Mayo Clinic, Radiation Oncology, Mayo Clinic School of Medicine Radiation Oncology, Jacksonville, USA

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  2. Samuel T. Chao

    1. Department of Radiation Oncology, Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, USA

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  3. Arjun Sahgal

    1. Sunnybrook Odette Cancer Centre, Department of Radiation Oncology, University of Toronto, Toronto, Canada

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  4. Jason P. Sheehan

    1. University of Virginia, Departments of Neurological Surgery and Radiation Oncology, Charlottesville, USA

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  • Offers a single, comprehensive resource for modern stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) techniques
  • Written by world renowned experts in radiation oncology and radiosurgery
  • Includes physics, clinical evidence, indications, and future directions for SRS and SBRT

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Table of contents (34 chapters)

  1. Front Matter

    Pages i-xix
    Download chapter PDF

  2. Radiobiology of Radiosurgery and Stereotactic Body Radiation Therapy

    1. Front Matter

      Pages 1-1
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    2. Vascular-Mediated Mechanisms and SRS/SBRT

      • Golnaz Farhat, Deepa Sharma, Gregory J. Czarnota
      Pages 3-13

    3. Radio-Immunology of Ablative Radiation

      • Talicia Savage, Chandan Guha
      Pages 15-29

    4. Rationale for Fractionated SRS and Single SRS Session Approaches

      • Jarred Tanksley, Joseph K. Salama, John P. Kirkpatrick
      Pages 31-40

  3. Intracranial Radiosurgery Technique

    1. Front Matter

      Pages 41-41
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    2. Physics of Radiosurgery

      • Yongsook C. Lee, Steven J. Goetsch, David J. Schlesinger, Stanley H. Benedict
      Pages 43-54

    3. Leksell Gamma Knife Radiosurgery

      • Diogo P. Cordeiro, David J. Schlesinger
      Pages 55-65

    4. CyberKnife Robotic Stereotactic Radiosurgery

      • Erqi Pollom, Lei Wang, Iris C. Gibbs, Scott G. Soltys
      Pages 67-76

    5. Linear Accelerator-Based Radiosurgery: Technique

      • William A. Friedman, Frank J. Bova
      Pages 77-82

    6. Fractionated Radiosurgery

      • Giuseppe Minniti, Claudia Scaringi
      Pages 83-90

    7. Charged-Particle Proton Radiosurgery

      • Arpit M. Chhabra, Mudit Chowdhary, Minesh P. Mehta
      Pages 91-101

  4. Intracranial Radiosurgery by Indication

    1. Front Matter

      Pages 103-103
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    2. Stereotactic Radiosurgery for Brain Metastases

      • Clayton Alonso, Jason P. Sheehan, Daniel M. Trifiletti
      Pages 105-111

    3. Stereotactic Radiosurgery for Pituitary Adenoma

      • Cheng-chia Lee, Daniel M. Trifiletti, Jason P. Sheehan
      Pages 113-121

    4. Stereotactic Radiosurgery for Meningioma

      • David R. Raleigh, Penny K. Sneed
      Pages 123-129

    5. Stereotactic Radiosurgery for Intracranial Arteriovenous Malformations

      • Jacqueline J. Tao, Justin Moore, Geoffrey Appelboom, Steven D. Chang
      Pages 131-140

    6. Radiosurgical Management of Trigeminal Neuralgia

      • Srinivas Chivukula, Nicholas Au Yong, Matiar Jafari, Nader Pouratian
      Pages 141-150

    7. Radiosurgery for Vestibular Schwannomas

      • Fabio Frisoli, Jugal Shah, Travis C. Hill, Douglas Kondziolka
      Pages 151-161

    8. Stereotactic Radiosurgery for Glial Tumors

      • Ajay Niranjan, L. Dade Lunsford
      Pages 163-171
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Keywords

About this book

This book is a comprehensive review of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT): its physics, clinical evidence, indications, and future directions. The utilization of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) is increasing internationally because of several factors. First, it offers patients a local treatment option that has demonstrated effectiveness similar to traditional surgery without the morbidity of general anesthesia and open surgical resection. Second, recent advancements in the quality of scientific evidence supporting a SRS or SBRT-containing approach in patients continues to evolve and demonstrate favorable disease-specific outcomes with little, if any, toxicity in various anatomic disease sites and for various conditions including cancer, benign tumors, and other psychiatric and neurologic conditions. Third, and most provocatively, is the notion that definitive local therapy (i.e. SRS or SBRT) in patients with cancer can boost the immune system to fight cancer in other sites throughout the body. While traditional medical knowledge would suggest that all patients with metastatic cancer are incurable, there is a mounting body of evidence that there is a subset of these patients that can be cured with definitive SRS or SBRT. This volume thus delves into each of these benefits and aspects of treatment, guiding physicians to the best treatment plan for their patients.

Expert, international authors provide guidelines for SRS and SBRT use by clinicians. Chapters are divided into six main sections: Radiobiology of Radiosurgery and Stereotactic Body Radiation Therapy, Intracranial  Radiosurgery Technique, Intracranial Radiosurgery by Indication, Stereotactic Body Radiation Therapy Technique, Stereotactic Body Radiation Therapy by Indication, The Future of Radiosurgery and SBRT. Overall physics are explained, as well as specific considerations for particular surgical tools (including the Leksell Gamma Knife and Accuray CyberKnife), techniques (including fractionated and charged particle radiosurgery), and anatomic sites (including brain metastases, pituitary tumors, and the prostate). Detailed images and charts enhance the chapters. This book provides physicians with a single, practical resource incorporating both of these broad categories of treatment, SRS and SBRT, and better defines the current role and the direction of radiosurgery.

Editors and Affiliations

  • Mayo Clinic, Radiation Oncology, Mayo Clinic School of Medicine Radiation Oncology, Jacksonville, USA

    Daniel M. Trifiletti

  • Department of Radiation Oncology, Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, USA

    Samuel T. Chao

  • Sunnybrook Odette Cancer Centre, Department of Radiation Oncology, University of Toronto, Toronto, Canada

    Arjun Sahgal

  • University of Virginia, Departments of Neurological Surgery and Radiation Oncology, Charlottesville, USA

    Jason P. Sheehan

About the editors

Daniel M. Trifiletti, MD is an Associate Professor of Radiation Oncology at The Mayo Clinic. He has won a number of awards related to his work in radiation oncology and has published extensively.

Samuel T. Chao, MD is an Associate Professor in the Department of Radiation Oncology at the Cleveland Clinic. He is also Director of CNS Radiation Oncology and Head of the Center for Cerebral Radiation Necrosis Brain Tumor and Neuro-Oncology Center at the Cleveland Clinic.

Arjun Sahgal, MD, FRCPC is an Associate Professor in the Department of Radiation Oncology and Surgery at the University of Toronto.

Jason P. Sheehan, MD, PhD is Professor of Neurological Surgery, Radiation Oncology, Biomedical Engineering and Neuroscience, and the Harrison Distinguished Teaching Chair of Neurosurgery at The University of Virginia, Health Sciences Center. There he is also the Neuroscience and Behavioral Science Medicine Service Line Director, Vice Chair of Academic Affairs in Neurological Surgery, Director of the Lars Leksell Gamma Knife Center, Co-Director of the UVa-Mary Washington Radiosurgery Center, Associate Residency Program Director, Director of Spinal Radiosurgery, and Co-medical Director of the UVa-Riverside Radiosurgery Center. He has published extensively in radiation oncology.

Bibliographic Information

  • Book Title: Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy

  • Book Subtitle: A Comprehensive Guide

  • Editors: Daniel M. Trifiletti, Samuel T. Chao, Arjun Sahgal, Jason P. Sheehan

  • DOI: https://doi.org/10.1007/978-3-030-16924-4

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-030-16923-7Published: 11 July 2019

  • Softcover ISBN: 978-3-030-16926-8Published: 15 August 2020

  • eBook ISBN: 978-3-030-16924-4Published: 27 June 2019

  • Edition Number: 1

  • Number of Pages: XIX, 435

  • Number of Illustrations: 20 b/w illustrations, 111 illustrations in colour

  • Topics: Radiotherapy

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