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  • Open Access
  • © 2019

Dilated Cardiomyopathy

From Genetics to Clinical Management

  • Open access comprehensive review of dilated cardiomyopathy, from pathophysiology to clinical management

  • Describes in detail differential diagnosis work-up for patients with non-ischemic cardiomyopathy

  • Highlights open issues such as the clinical use of genetic testing and arrhythmia in dilated cardiomyopathy

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-ix
  2. Historical Terminology, Classifications, and Present Definition of DCM

    • Marco Merlo, Chiara Daneluzzi, Luisa Mestroni, Antonio Cannatà, Gianfranco Sinagra
    Pages 1-9Open Access
  3. Epidemiology

    • Paola Naso, Luca Falco, Aldostefano Porcari, Andrea Di Lenarda, Gerardina Lardieri
    Pages 11-16Open Access
  4. Pathophysiology

    • Valerio De Paris, Federico Biondi, Davide Stolfo, Marco Merlo, Gianfranco Sinagra
    Pages 17-25Open Access
  5. Etiological Definition and Diagnostic Work-Up

    • Marco Merlo, Marco Gobbo, Jessica Artico, Elena Abate, Stefania Franco
    Pages 27-43Open Access
  6. Genetics of Dilated Cardiomyopathy: Current Knowledge and Future Perspectives

    • Matteo Dal Ferro, Giovanni Maria Severini, Marta Gigli, Luisa Mestroni, Gianfranco Sinagra
    Pages 45-69Open Access
  7. Clinical Presentation, Spectrum of Disease, and Natural History

    • Marco Merlo, Davide Stolfo, Thomas Caiffa, Alberto Pivetta, Gianfranco Sinagra
    Pages 71-82Open Access
  8. Role of Cardiac Imaging: Echocardiography

    • Bruno Pinamonti, Elena Abate, Antonio De Luca, Gherardo Finocchiaro, Renata Korcova
    Pages 83-111Open Access
  9. Role of Cardiac Imaging: Cardiac Magnetic Resonance and Cardiac Computed Tomography

    • Giancarlo Vitrella, Giorgio Faganello, Gaetano Morea, Lorenzo Pagnan, Manuel Belgrano, Maria Assunta Cova
    Pages 113-133Open Access
  10. Endomyocardial Biopsy

    • Rossana Bussani, Furio Silvestri, Andrea Perkan, Piero Gentile, Gianfranco Sinagra
    Pages 135-147Open Access
  11. Arrhythmias in Dilated Cardiomyopathy: Diagnosis and Treatment

    • Massimo Zecchin, Daniele Muser, Laura Vitali-Serdoz, Alessandra Buiatti, Tullio Morgera
    Pages 149-171Open Access
  12. Regenerative Medicine and Biomarkers for Dilated Cardiomyopathy

    • Pierluigi Lesizza, Aneta Aleksova, Benedetta Ortis, Antonio Paolo Beltrami, Mauro Giacca, Gianfranco Sinagra
    Pages 173-185Open Access
  13. Prognostic Stratification and Importance of Follow-Up

    • Antonio Cannatà, Davide Stolfo, Marco Merlo, Cosimo Carriere, Gianfranco Sinagra
    Pages 187-198Open Access
  14. Current Management and Treatment

    • Alessandro Altinier, Alessia Paldino, Marta Gigli, Aniello Pappalardo, Gianfranco Sinagra
    Pages 199-215Open Access
  15. Unresolved Issues and Future Perspectives

    • Marco Merlo, Giulia De Angelis, Antonio Cannatà, Laura Massa, Gianfranco Sinagra
    Pages 217-227Open Access
  16. Dilated Cardiomyopathy at the Crossroad: Multidisciplinary Approach

    • Gianfranco Sinagra, Enrico Fabris, Simona Romani, Francesco Negri, Davide Stolfo, Francesca Brun et al.
    Pages 229-241Open Access

About this book

This open access book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease’s pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment interaction. The second part presents current and future treatment options, highlighting the importance of long-term and individualized treatments and follow-up.
Furthermore, it discusses open issues, such as the apparent healing phenomenon, the early prognosis of arrhythmic events or the use of genetic testing in clinical practice.

Offering a multidisciplinary approach for optimizing the clinical management of DCM, this book is an invaluable aid not only for the clinical cardiologists, but for all physicians involved in the care of this challenging disease.  

Editors and Affiliations

  • Cardiovascular Department, Azienda Sanitaria Universitaria Integrata, Trieste, Italy

    Gianfranco Sinagra, Marco Merlo, Bruno Pinamonti

About the editors

Gianfranco Sinagra is a full professor of Cardiology at University of Trieste and director of the Cardiovascular Department of the University Hospital Azienda Sanitaria Universitaria Integrata, Trieste, Italy, a centre of reference for the diagnosis and treatment of cardiomyopathies. He is author of more than 350 peer-reviewed international publications and several books, mostly on prognostic stratification, analysis of subgroups and reviews on dilated cardiomyopathy, arrhythmogenic cardiomyopathies and myocarditis. He is editor of following Springer books “Genetic Cardiomyopathies” (2013) and “Clinical Echocardiography and Other Imaging Techniques in Cardiomyopathies” (2014).

Marco Merlo is chief of the Clinical Research of Cardiovascular Department and of Heart Muscle Disease Registry of Trieste,  that currently enrolls  more than 2000 cardiomyopathy patients,  1200 of which are affected by dilated cardiomyopathy.  His expertise covers the management of cardiomyopathy outpatients as well as inpatients. He is author of more than 70 peer-reviewed international publications, mostly on prognostic stratification, analysis of subgroups and reviews on dilated cardiomyopathy, arrhythmogenic cardiomyopathies and myocarditis.

 Bruno Pinamonti is chief of the Echo Lab at the Cardiovascular Department of Trieste. He is an international expert on echo imaging in cardiomyopathies, specialized in dilated cardiomyopathy, arrhythmogenic cardiomyopathy and myocarditis. He is author of more than 120 peer-reviewed international publications and several books, mostly on prognostic stratification, analysis of subgroups on dilated cardiomyopathy, arrhythmogenic cardiomyopathies and myocarditis, including the Springer book “Clinical Echocardiography and Other Imaging Techniques in Cardiomyopathies” (2014).

 All Editors have published peer-reviewed papers about cardiomyopathies in the major international medical journals, such as the New England Journal of Medicine,  the Journal of American College of Cardiology, Circulation and the European Heart Journal.

Bibliographic Information

  • Book Title: Dilated Cardiomyopathy

  • Book Subtitle: From Genetics to Clinical Management

  • Editors: Gianfranco Sinagra, Marco Merlo, Bruno Pinamonti

  • DOI: https://doi.org/10.1007/978-3-030-13864-6

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s) 2019

  • License: CC BY

  • Hardcover ISBN: 978-3-030-13863-9Published: 28 May 2019

  • Softcover ISBN: 978-3-030-13866-0Published: 15 August 2020

  • eBook ISBN: 978-3-030-13864-6Published: 17 May 2019

  • Edition Number: 1

  • Number of Pages: IX, 241

  • Number of Illustrations: 10 b/w illustrations, 45 illustrations in colour

  • Topics: Cardiology, Cardiac Imaging, Human Genetics, Regenerative Medicine/Tissue Engineering

Buy it now

Buying options

Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 59.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access