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  • © 2019

Reviews on Biomarker Studies of Metabolic and Metabolism-Related Disorders

Editors:

  • Discusses both positive and negative findings
  • Describes studies of diseases not commonly thought of as having metabolic links or origins
  • Looks at economic aspects of these diseases and the benefits of using biomarkers for the healthcare systems

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1134)

Part of the book sub series: Proteomics, Metabolomics, Interactomics and Systems Biology (PMISB)

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xi
  2. Insulin Resistance in Schizophrenia

    • Paul C. Guest
    Pages 1-16
  3. Targeting Mitochondrial Defects to Increase Longevity in Animal Models of Neurodegenerative Diseases

    • Ester Casajus Pelegay, Francesco Puzzo, Acelya Yilmazer, Umut Cagin
    Pages 89-110
  4. miRNA Regulation of Glucose and Lipid Metabolism in Relation to Diabetes and Non-alcoholic Fatty Liver Disease

    • Tanapa Suksangrat, Phatchariya Phannasil, Sarawut Jitrapakdee
    Pages 129-148
  5. Hypercaloric Diet-Induced Obesity and Obesity-Related Metabolic Disorders in Experimental Models

    • Natália Pinheiro-Castro, Lívia Beatriz Aparecida Ribeiro Silva, Gabriela Machado Novaes, Thomas Prates Ong
    Pages 149-161
  6. Metabolic Biomarkers in Nematode C. elegans During Aging

    • Sumino Yanase, Takamasa Ishii, Kayo Yasuda, Naoaki Ishii
    Pages 163-175
  7. Deciphering Endothelial Dysfunction in the HIV-Infected Population

    • Genevieve Mezoh, Nigel J. Crowther
    Pages 193-215
  8. PFKP Signaling at a Glance: An Emerging Mediator of Cancer Cell Metabolism

    • Liwei Lang, Ron Chemmalakuzhy, Chloe Shay, Yong Teng
    Pages 243-258
  9. ATAD3A on the Path to Cancer

    • Yong Teng, Liwei Lang, Chloe Shay
    Pages 259-269
  10. Back Matter

    Pages 295-303

About this book

The book recognizes that throughout the scientific, medical, and economic communities, new tests incorporating biomarkers are needed to improve the diagnosis of patients suffering from metabolic disorders. The early identification of those at risk of developing obesity will help to place these individuals on the best treatment course as early as possible for improved treatment outcomes. This will also help to cut costs incurred by the healthcare services. For all of this to occur, new research efforts are needed to identify novel biomarkers that can be used to predict the disease in the presymptomatic stage, for disease monitoring and for prediction of treatment response. It is also possible that new drug targets can be identified using these approaches which, in turn, can lead to the development of new treatment approaches. This volume also includes a series of reviews on biomarker discovery and usage in the study of diseases marked by perturbations in metabolism. It will describe the pros and cons of the various approaches and cover the successes and failures in this important research field.

Editors and Affiliations

  • Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil

    Paul C. Guest

About the editor

Dr Paul C. Guest, Ph.D, is a scientific researcher/writer with 35 years of experience in the fields of metabolic and neurological disorders. This includes experience in both academia and the pharmaceutical industry with the majority of time spent at the University of Cambridge and Merck Sharp & Dohme in the United Kingdom. He has also been affiliated with the University of Campinas in Sao Paulo Brazil since 2015, still focused on advancing the field of biomarkers for neurological disorders such as schizophrenia and Alzheimer’s disease.

Bibliographic Information

  • Book Title: Reviews on Biomarker Studies of Metabolic and Metabolism-Related Disorders

  • Editors: Paul C. Guest

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-030-12668-1

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-030-12667-4Published: 08 April 2019

  • Softcover ISBN: 978-3-030-12670-4Published: 14 August 2020

  • eBook ISBN: 978-3-030-12668-1Published: 27 March 2019

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XI, 303

  • Number of Illustrations: 17 b/w illustrations, 22 illustrations in colour

  • Topics: Proteomics, Gene Function, Diabetes

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access