Overview
- Bridges material science at the nanoscale with biological matter and its functions
- Focuses on molecular and cellular aspects
- Helps scholars from various disciplines to get acquainted with the bio-nano field
Part of the book series: NanoScience and Technology (NANO)
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Table of contents (13 chapters)
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Front Matter
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Manufacturing and Characterization of Materials
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Front Matter
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Membrane Transfer, Cellular Uptake and Intracellular Fate: Mechanisms and Detection Methods
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Front Matter
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Cellular Responses and Health Effects
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Front Matter
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Back Matter
Keywords
About this book
In this book the recent progress accumulated in studies of the interaction of engineered nanoparticles with cells and cellular constituents is presented. The focus is on manufacturing and characterization of nanosized materials, their interactions with biological molecules such as proteins, the mechanisms of transport across biological membranes as well as their effects on biological functions. Fundamental molecular and cellular aspects are in the foreground of the book. A further particularity is the interdisciplinary approach, including fields such as preparatory and analytical chemistry, biophysics and the physics of colloids, advanced microscopy and spectroscopy for in-situ detection of nanoparticles, cellular toxicology and nanomedicine.
Nanoscale particles are known to exhibit novel and unprecedented properties that make them different from their corresponding bulk materials. As our ability to control these properties is further advanced, a huge potential to create materials with novel properties and applications emerges. Although the technological and economic benefits of nanomaterials are indisputable, concerns have also been raised that nanoscale structuring of materials might also induce negative health effects. Unfortunately, such negative health effects cannot be deduced from the known toxicity of the corresponding macroscopic material. As a result, there is a major gap in the knowledge necessary for assessing their risk to human health.
Editors and Affiliations
Bibliographic Information
Book Title: Biological Responses to Nanoscale Particles
Book Subtitle: Molecular and Cellular Aspects and Methodological Approaches
Editors: Peter Gehr, Reinhard Zellner
Series Title: NanoScience and Technology
DOI: https://doi.org/10.1007/978-3-030-12461-8
Publisher: Springer Cham
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: Springer Nature Switzerland AG 2019
Hardcover ISBN: 978-3-030-12460-1Published: 26 April 2019
Softcover ISBN: 978-3-030-12463-2Published: 29 October 2020
eBook ISBN: 978-3-030-12461-8Published: 16 April 2019
Series ISSN: 1434-4904
Series E-ISSN: 2197-7127
Edition Number: 1
Number of Pages: XX, 344
Number of Illustrations: 31 b/w illustrations, 40 illustrations in colour
Topics: Biological and Medical Physics, Biophysics, Nanochemistry, Cell Biology, Nanotechnology, Biomedical Engineering and Bioengineering