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Cluster Headache and other Trigeminal Autonomic Cephalgias

  • Reviews recent advances in cluster headache and trigeminal autonomic cephalgias
  • Explains the neurobiology of various headache forms
  • Examines current and future approaches to treatment

Part of the book series: Headache (HEAD)

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-x
  2. Cluster Headache and Related Syndromes in History and Literature

    • Gian Camillo Manzoni, Paola Torelli
    Pages 1-6
  3. Epidemiology of Cluster Headache

    • Michael Bjørn Russell
    Pages 7-10
  4. Classification and Clinical Features

    • Pietro Cortelli, Sabina Cevoli, Jesica Garcia, Miguel J. A. Láinez
    Pages 11-21
  5. Differential Diagnosis, Including Secondary Forms

    • Patricia Pozo-Rosich, Alessandro S. Zagami
    Pages 23-41
  6. Genetics of Cluster Headache and Other Trigeminal Autonomic Cephalalgias

    • Arn M. J. M. van den Maagdenberg, Anne Ducros
    Pages 43-56
  7. Neuroimaging in Cluster Headache and Trigeminal Autonomic Cephalalgias

    • Laura H. Schulte, Stefania Ferraro
    Pages 67-90
  8. Some Observations About the Origin of the Pain in Cluster Headache

    • Trine Nielsen, Arne May, Tim P. Jürgens
    Pages 91-101
  9. Animals Models for Trigeminal Autonomic Cephalalgias

    • Simon Akerman, Cristina Tassorelli
    Pages 103-115
  10. Acute Treatment of Cluster Headache Attacks

    • Stefan Evers
    Pages 131-134
  11. Prophylactic Drugs

    • Andrea Negro, Paolo Martelletti
    Pages 135-151
  12. Neurostimulation: Why, When, and Which One?

    • Michel Lantéri-Minet, Denys Fontaine, Delphine Magis
    Pages 153-167
  13. Behavioral and Psychological Aspects, Quality of Life, and Disability and Impact of Cluster Headache

    • Lauren Ashley-Marie Schenck, Alberto Raggi, Domenico D’Amico, Alberto Proietti Cecchini, Frank Andrasik
    Pages 169-187
  14. Neurophysiology of Cluster Headache and Other Trigeminal Autonomic Cephalalgias

    • Gianluca Coppola, Armando Perrotta, Francesco Pierelli, Giorgio Sandrini
    Pages 189-208
  15. Trigeminal Neuralgia: Channels, Pathophysiology, and Therapeutic Challenges

    • Daniele Cazzato, Stine Maarbjerg, Lars Bendtsen, Giuseppe Lauria
    Pages 209-219
  16. Migraine and Cluster Headache: Differences and Similarities

    • Fu-Chi Yang, Todd J. Schwedt, Shuu-Jiun Wang
    Pages 221-236
  17. The Short-Lasting Headaches Including Hypnic Headache

    • Anna Cohen, Giorgio Lambru
    Pages 237-255

About this book

This book provides essential insights into the current state of knowledge regarding the main aspects of cluster headache and trigeminal autonomic cephalgias. The first chapters focus on classification and clinical features, together with familial and genetic aspects. Relevant animal models and the putative role of key nervous structures as the hypothalamus, brainstem, diencephalon and sphenopalatine ganglion are reviewed.  Evidence gained from key molecules such as CGRP in animals and human headache models are discussed.

The book subsequently presents information on the various aspects of the pathophysiology of trigeminal autonomic cephalalgias for example regarding the implication of the trigeminovascular system and the facial autonomic reflexes of the brainstem. Further, it shares insights from imaging studies including functional magnetic resonance imaging and more advanced techniques, as well as brain stimulation procedures. Further chapters describe the current st

ate of knowledge concerning drug treatment and the various neurostimulation procedures. Trigeminal neuralgia is also presented, due its close relationship with some short-term trigeminal autonomic cephalgias: a great deal can be learned from a better understanding of their differences and similarities. The same approach is then applied to cluster headache and migraine.

All chapters were written by respected experts in their fields, ensuring the book will provide an excellent source of up-to-date information and perspectives on trigeminal autonomic cephalgias and related disorders.  As such, it will be of considerable value for students, clinicians and pain researchers alike.

Reviews

“This book is meant for ‘young neurologists and doctors,’ as well as neuroscience researchers. The book meets the needs of this audience, since the depth at which it examines cluster headache and TACs is appropriate for neurologists and those in research. … This is a wonderful resource for those treating patients with cluster headache or TACs. … It is a useful resource for those tasked with caring for these patients.” (Aliza Sharon Kumpinsky, Doody's Book Reviews, November 08, 2019)

Editors and Affiliations

  • Department of Neurology, Neuroalgology Unit, The Foundation of the Carlo Besta Neurological Institute, IRCCS, Milano, Italy

    Massimo Leone

  • Department of Systems Neuroscience, University of Hamburg, Hamburg, Germany

    Arne May

About the editors

Massimo Leone has been a neurologist at Carlo Besta Neurological Institute since 1985. Throughout the years he has helped to introduce the main treatments for cluster headache and other trigeminal autonomic cephalgias, including verapamil. He has been recognized by various Institutions for the introduction of deep brain stimulation in cluster headache and other trigeminal autonomic cephalgias, and has published 270 original articles. Since 2007 he has led the Neuromodulation Unit of the Neurological Department, Headache and Neuroalgology Centre at Carlo Besta Neurological Institute.

 Arne May is a Professor of Neurology at the Department of Systems Neuroscience, University of Hamburg and head of the headache outpatient clinic and the facial outpatient clinic of the University Clinic of Hamburg. His major research interests are the basic mechanisms of facial and head pain, the chronification of pain and plasticity within the human brain. His group’s work involves humanimaging studies in primary headache as well as experimental studies of trigeminovascular nociception, with the aim of understanding how to modulate facial and headache syndromes and chronicity of pain. Prior to his position at the University of Hamburg, Professor May was a clinician and conducted research on pain and headache syndromes at the University of Regensburg. Prior to this he completed his residency in the Neurology Department of the University of Essen, followed by post-doctorate studies at the Institute of Neurology in London. Professor May has been a member of the Board of Trustees of the International Headache Society since 2013, and has published over 300 original and review articles.

Bibliographic Information

  • Book Title: Cluster Headache and other Trigeminal Autonomic Cephalgias

  • Editors: Massimo Leone, Arne May

  • Series Title: Headache

  • DOI: https://doi.org/10.1007/978-3-030-12438-0

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-12437-3Published: 05 August 2019

  • Softcover ISBN: 978-3-030-12440-3Published: 15 August 2020

  • eBook ISBN: 978-3-030-12438-0Published: 17 July 2019

  • Series ISSN: 2197-652X

  • Series E-ISSN: 2197-6538

  • Edition Number: 1

  • Number of Pages: X, 264

  • Number of Illustrations: 2 b/w illustrations, 3 illustrations in colour

  • Topics: Internal Medicine, Neurology, Pain Medicine

Buy it now

Buying options

eBook USD 49.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 64.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 89.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access