Overview
- Editors:
-
-
Maurizio De Pittà
-
Group of Mathematical, Computational and Experimental Neuroscience, Basque Center for Applied Mathematics, Bilbao, Biscay, Spain
-
Hugues Berry
-
INRIA Rhône-Alpes, Université de Lyon, Villeurbanne, Lyon, France
- The first systematic computational approach to neuron-glia interactions
- Presents a "conversation" between experimentalists and theoreticians
- Explores a series of hot topics in glia research
Access this book
Other ways to access
Table of contents (18 chapters)
-
-
Introduction
-
-
- Maurizio De Pittà, Hugues Berry
Pages 3-35
-
Calcium Dynamics
-
-
- Ivo Siekmann, Pengxing Cao, James Sneyd, Edmund J. Crampin
Pages 39-68
-
-
- Sten Rüdiger, Jianwei Shuai
Pages 91-114
-
- Maurizio De Pittà, Eshel Ben-Jacob, Hugues Berry
Pages 115-150
-
- Valeri Matrosov, Susan Gordleeva, Natalia Boldyreva, Eshel Ben-Jacob, Victor Kazantsev, Maurizio De Pittà
Pages 151-176
-
- Jules Lallouette, Maurizio De Pittà, Hugues Berry
Pages 177-210
-
Tripartite Synapse and Regulation of Network Activity
-
Front Matter
Pages 211-211
-
- Candela González-Arias, Gertrudis Perea
Pages 213-226
-
- Anup Pillai, Suhita Nadkarni
Pages 227-244
-
-
- Vladislav Volman, Maxim Bazhenov
Pages 289-305
-
Homeostasis and Metabolic Coupling
-
Front Matter
Pages 309-309
-
-
- Konstantin Mergenthaler, Franziska Oschmann, Klaus Obermeyer
Pages 329-361
-
- Geir Halnes, Klas H. Pettersen, Leiv Øyehaug, Marie E. Rognes, Gaute T. Einevoll
Pages 363-391
-
About this book
Over the last two decades, the recognition that astrocytes - the predominant type of cortical glial cells - could sense neighboring neuronal activity and release neuroactive agents, has been instrumental in the uncovering of many roles that these cells could play in brain processing and the storage of information. These findings initiated a conceptual revolution that leads to rethinking how brain communication works since they imply that information travels and is processed not just in the neuronal circuitry but in an expanded neuron-glial network. On the other hand the physiological need for astrocyte signaling in brain information processing and the modes of action of these cells in computational tasks remain largely undefined. This is due, to a large extent, both to the lack of conclusive experimental evidence, and to a substantial lack of a theoretical framework to address modeling and characterization of the many possible astrocyte functions. This book that we propose aims at filling this gap, providing the first systematic computational approach to the complex, wide subject of neuron-glia interactions. The organization of the book is unique insofar as it considers a selection of “hot topics” in glia research that ideally brings together both the novelty of the recent experimental findings in the field and the modelling challenge that they bear. A chapter written by experimentalists, possibly in collaboration with theoreticians, will introduce each topic. The aim of this chapter, that we foresee less technical in its style than in conventional reviews, will be to provide a review as clear as possible, of what is “established” and what remains speculative (i.e. the open questions). Each topic will then be presented in its possible different aspects, by 2-3 chapters by theoreticians. These chapters will be edited in order to provide a “priming” reference for modeling neuron-glia interactions, suitable both for the graduate student and the professional researcher.
Editors and Affiliations
-
Group of Mathematical, Computational and Experimental Neuroscience, Basque Center for Applied Mathematics, Bilbao, Biscay, Spain
Maurizio De Pittà
-
INRIA Rhône-Alpes, Université de Lyon, Villeurbanne, Lyon, France
Hugues Berry
