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  • © 1996

Multiple Sclerosis

Advances in Clinical Trial Design, Treatment and Future Perspectives

  • Covers the important new developments in clinical trial design and a number of important trial results that have resulted in new treatment options for patients and physicians *
  • Important ethical considerations that arise with new treatments are included, as is a perspective on the emergence of MS as a treatable disease * Will be of interest to both specialists and general practitioners alike * Also will be of value to clinical epidemiologists and biostatisticians with an interest in experimental therapies for chronic disease, to immunologists with an interest in autoimmune disease, and to the pharmaceutical industry and to Multiple Sclerosis societies

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xviii
  2. Pathogenesis of Multiple Sclerosis: Relationship to Therapeutic Strategies

    • Jorge R. Oksenberg, Stephen L. Hauser
    Pages 17-46
  3. Clinical Outcome Measures for Multiple Sclerosis

    • Brian G. Weinshenker
    Pages 105-122
  4. “Quality of Life” Assessment in Multiple Sclerosis Clinical Trials: Current Status and Strategies for Improving Multiple Sclerosis Clinical Trial Design

    • Nicholas G. LaRocca, Paul G. Ritvo, Deborah M. Miller, Jill S. Fischer, Howard Andrews, Donald W. Paty
    Pages 145-160
  5. Treatment of Multiple Sclerosis with Type I Interferons

    • Richard A. Rudick, William Sibley, Luca Durelli
    Pages 223-250
  6. Treatment of Multiple Sclerosis with Methotrexate

    • Donald E. Goodkin, Jill S. Fischer
    Pages 251-287
  7. Treatment of Multiple Sclerosis with Copolymer 1

    • Kenneth P. Johnson, M. B. Bornstein
    Pages 289-312
  8. Treatment of Multiple Sclerosis with Cladribine

    • Jack C. Sipe, J. S. Romine, J. Zyroff, J. Koziol, E. Beutler
    Pages 313-334
  9. Back Matter

    Pages 361-364

About this book

Multiple Sclerosis: Advances in Clinical Trial Design, Treatment and Future Perspectives is a review of therapeutic developments for a disease that is one of the major problems in current neurologic practice. Progress in this field has been rapid and there have been important developments in clinical trial design and a number of important trial results that have resulted in new treatment options for patients and physicians. Important ethical considerations that arise with new treatments are included, as is a perspective on the emergence of MS as a treatable disease. This book is for all neurologists, primary care physicians, and patients concerned about the treatment of MS. It will also be of value to clinical epidemiologists and biostatisticians with an interest in experimental therapies for chronic disease, to immunologists with an interest in autoimmune disease, to the pharmaceutical industry and to MS societies.

Editors and Affiliations

  • The UCSF/Mount Zion Multiple Sclerosis Center, University of California at San Francisco, San Francisco, USA

    Donald E. Goodkin

  • Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic Foundation, Cleveland, USA

    Richard A. Rudick

Bibliographic Information

  • Book Title: Multiple Sclerosis

  • Book Subtitle: Advances in Clinical Trial Design, Treatment and Future Perspectives

  • Editors: Donald E. Goodkin, Richard A. Rudick

  • DOI: https://doi.org/10.1007/978-1-4471-1271-6

  • Publisher: Springer London

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag London Limited 1996

  • Softcover ISBN: 978-1-85233-033-0Published: 26 May 1998

  • eBook ISBN: 978-1-4471-1271-6Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVIII, 364

  • Number of Illustrations: 4 b/w illustrations

  • Topics: Neurology, Internal Medicine, General Practice / Family Medicine

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access