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  • © 2001

Clinical Trials in Neurology

  • Drug companies rely on trials to show the efficacy or problems relating to new drugs

  • This new multi-contributor book aims to improve the efficacy of neurological trials by improving trial design

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Table of contents (41 chapters)

  1. Front Matter

    Pages i-xvii
  2. General

    1. Front Matter

      Pages 1-1
    2. Ethical Considerations

      • T. Hope, J. Savulescu
      Pages 3-15
    3. Assessment Measures and Clinical Scales

      • J. C. Hobart, A. J. Thompson
      Pages 17-28
    4. Drug Development Stages

      • T. G. K. Mant
      Pages 53-58
    5. Analysis of Results: Statistical Principles

      • D. Hoberman, J. T. Sahlroot
      Pages 105-120
    6. Survival Analysis

      • R. Newson
      Pages 121-129
    7. The Intention-to-Treat Principle for Clinical Trials

      • M. J. Schell, M. A. McBride, C. Gennings, G. G. Koch
      Pages 131-143
  3. Diseases

    1. Front Matter

      Pages 169-169
    2. Outcome Variables in Dementia Trials: Conceptual and Practical Issues

      • A. D. Lawrence, B. J. Sahakian
      Pages 171-182

About this book

Clinical Trials in Neurology comprehensively tackles the methodology and design of clinical trials in neurological disease. A general section deals with the ethical aspects, drug development and regulatory requirements, basic trial designs and the statistics used. A diseases section tackles specific aspects of disorders, focusing on the relevant ethical issues, outcome variables and experience with large multicentre trials.

Editors and Affiliations

  • Neuromuscular Unit, West London Neurosciences Centre, 1st Floor Pilot Wing, Charing Cross Hospital, London, UK

    Roberto J. Guiloff

Bibliographic Information

  • Book Title: Clinical Trials in Neurology

  • Editors: Roberto J. Guiloff

  • DOI: https://doi.org/10.1007/978-1-4471-3787-0

  • Publisher: Springer London

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag London 2001

  • Hardcover ISBN: 978-1-85233-239-6Published: 05 May 2001

  • Softcover ISBN: 978-1-84996-856-0Published: 13 October 2010

  • eBook ISBN: 978-1-4471-3787-0Published: 14 March 2013

  • Edition Number: 1

  • Number of Pages: XVIII, 542

  • Topics: Neurology, Pharmacology/Toxicology

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 299.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access