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Management of Myocardial Reperfusion Injury

  • Book
  • © 2012

Overview

Editors:
  1. Juan Carlos Kaski

    1. Medical School, Coronary Artery Disease, Research Group, St George's Hospital, London, United Kingdom

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  2. Derek J. Hausenloy

    1. Hatter Cardiovascular Inst., Div. Medicine, University College London, London, United Kingdom

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  3. Bernard John Gersh

    1. Mayo Graduate School of Medicine, Dept. Cardiovascular Diseases, Mayo Clinic, Rochester, USA

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  4. Derek M. Yellon

    1. Hatter Cardiovascular Institute, University College London, London, United Kingdom

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  • Proposed editors are top scientists and clinicians in their field

  • Suggested contributors are also recognised experts

  • A publication deals with integral diagnostic strategies

  • Book presented in a modern and systematic way

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xv
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  2. Introduction

    1. Front Matter

      Pages 1-1
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    2. Myocardial Reperfusion Injury as a New Frontier for Clinical Therapy

      • Derek J. Hausenloy, Juan Carlos Kaski, Bernard John Gersh, Derek M. Yellon
      Pages 3-8

  3. The Pathophysiology of Myocardial Reperfusion Injury: From a Pre-clinical Phenomenon to a New Target for Cardioprotection

    1. Front Matter

      Pages 9-9
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  4. The Pathophysiology of Myocardial Reperfusion Injury:From a Pre-Clinical Phenomenon to a New Target for Cardioprotection

    1. Pathophysiology of Myocardial Reperfusion Injury

      • James M. Downey, Michael V. Cohen
      Pages 11-28

    2. Microvascular Obstruction: The No-Reflow Phenomenon in Animal Models of Myocardial Ischemia and Reperfusion

      • Thorsten Reffelmann, Robert A. Kloner
      Pages 29-50

    3. Lethal Myocardial Reperfusion Injury

      • Jakob Vinten-Johansen, Amanda J. Zatta, Rong Jiang, Weiwei Shi
      Pages 51-85

    4. Translating Cardioprotective Strategies into Clinical Settings

      • Nathan Mewton, François Roubille, Olivier Lairez, Gilles Rioufol, Meyer Elbaz, Christophe Piot et al.
      Pages 87-99

  5. Diagnosis of Myocardial Reperfusion Injury: Assessment and Quantification

    1. Front Matter

      Pages 101-101
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  6. Diagnosis of Myocardial Reperfusion Injury: Assessment and Quantification

    1. Cardiac Catheter Laboratory

      • Eva von Schmilowski, Howard Swanton
      Pages 103-133

    2. Echocardiography in Myocardial Reperfusion Injury

      • Mariana Mirabel, Denis Pellerin
      Pages 135-159

    3. Nuclear Imaging to Assess Infarction, Reperfusion, No-Reflow, and Viability

      • Victoria Delgado, Arend F. L. Schinkel, Kai-Hang Yiu, Jeroen J. Bax
      Pages 161-189

    4. Role of Cardiovascular Magnetic Resonance in the Assessment of Patients with Acute Myocardial Infarction

      • Andreas Kumar, Matthias G. Friedrich
      Pages 191-212

  7. Management of Myocardial Reperfusion Injury

    1. Front Matter

      Pages 213-213
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    2. Current Approaches to Prevention and Management of Reperfusion Injury

      • Wichert J. Kuijt, Judson Williams, Christopher B. Granger, Mitchell W. Krucoff, Matthew T. Roe
      Pages 215-238

    3. Endogenous Cardioprotective Strategies

      • Abhiram Prasad, Bernard John Gersh
      Pages 239-260

    4. Novel Treatment Strategies

      • Derek J. Hausenloy, Derek M. Yellon
      Pages 261-291

    5. Future Perspectives

      • Derek J. Hausenloy, Juan Carlos Kaski, Bernard John Gersh, Derek M. Yellon
      Pages 293-295

  8. Back Matter

    Pages 297-305
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Keywords

About this book

Much has been written about reperfusion injury in the past decade but unfortunately the information has been generally presented in the form of original specialist papers and little if any integral publication exists on the topic, summarising and analysing the clinical impact of the condition and its management. The pathophysiology and molecular mechanisms of reperfusion injury are complex and, regarding diagnosis, individual diagnostic techniques have been proposed but without a proper assessment of the relative values of these methods. A publication dealing with integral diagnostic strategies would be welcome by the managing physician. Management of the condition is also problematic, as strategies that appear to work in the experimental models do not translate into beneficial interventions in patients. There is a need for these issues to be addressed and discussed in a monographic fashion. Management of Myocardial Reperfusion Injury will tackle these issues in a modern and systematic way and the information will be delivered in a fashion that will be appealing to the reader.

Editors and Affiliations

  • Medical School, Coronary Artery Disease, Research Group, St George's Hospital, London, United Kingdom

    Juan Carlos Kaski

  • Hatter Cardiovascular Inst., Div. Medicine, University College London, London, United Kingdom

    Derek J. Hausenloy

  • Mayo Graduate School of Medicine, Dept. Cardiovascular Diseases, Mayo Clinic, Rochester, USA

    Bernard John Gersh

  • Hatter Cardiovascular Institute, University College London, London, United Kingdom

    Derek M. Yellon

Bibliographic Information

  • Book Title: Management of Myocardial Reperfusion Injury

  • Editors: Juan Carlos Kaski, Derek J. Hausenloy, Bernard John Gersh, Derek M. Yellon

  • DOI: https://doi.org/10.1007/978-1-84996-019-9

  • Publisher: Springer London

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag London 2012

  • Hardcover ISBN: 978-1-84996-018-2Published: 21 July 2012

  • Softcover ISBN: 978-1-4471-5813-4Published: 09 August 2014

  • eBook ISBN: 978-1-84996-019-9Published: 20 July 2012

  • Edition Number: 1

  • Number of Pages: XVI, 308

  • Topics: Cardiology, Cardiac Surgery

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