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  • Book
  • © 2009

Bone and Cancer

  • With chapters written by authorities in the field, the reader will be made aware of the current status of the disease, appropriate treatment and a sense of where future research is likely to lead
  • Includes supplementary material: sn.pub/extras

Part of the book series: Topics in Bone Biology (TBB, volume 5)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xviii
  2. Blood–Bone Axis and Bone Marrow Microenvironment

    • Aaron M. Havens, Yusuke Shiozawa, Russell S. Taichman
    Pages 1-17
  3. Genetics of Osteosarcoma

    • Marc F. Hansen
    Pages 19-42
  4. Multiple Myeloma and Other Hematological Malignancies of Bone

    • Rajesh Sehgal, Kristen Sanfilippo, G. David Roodman
    Pages 43-56
  5. Mechanism of Metastasis to Bone: The Role of Bone Marrow Endothelium

    • Carlton R. Cooper, Robert A. Satcher, Lisa A. Gurski, Kenneth L. van Golen
    Pages 57-71
  6. Lysophosphatidic Acid: Role in Bone and Bone Cancer

    • Olivier Peyruchaud, Norman J. Karin
    Pages 73-88
  7. Role of Bone Microenvironment/Metastatic Niche in Cancer Progression

    • Anna Podolanczuk, Bethan Psaila, David Lyden
    Pages 89-101
  8. Detection and Characterization of Disseminated Tumor Cells present in Bone Marrow of Cancer Patients

    • Sabine Riethdorf, Volkmar Müller, Catherine Alix-Panabières, Klaus Pantel
    Pages 103-117
  9. Molecular Imaging of Cancer Cells Growing in Bone

    • Inna Serganova, Ronald G. Blasberg
    Pages 119-140
  10. Inflammatory Cytokines and Their Role in Bone Metastasis and Osteolysis

    • Larry J. Suva, Richard W. Nicholas, Dana Gaddy
    Pages 141-155
  11. Prostate Cancer Bone Colonization: Osteomimicry in the Bone Niche

    • Leland W.K. Chung, Haiyen E. Zhau, John A. Petros, Mary C. Farach-Carson
    Pages 157-166
  12. Bone Pain Associated with Cancer Metastasis

    • Patrick W. O’Donnell, Nancy M. Luger, Denis R. Clohisy
    Pages 167-179
  13. Small Animal Models for the Study of Cancer in Bone

    • David J. DeGraff, Fayth L. Miles, Ronald R. Gomes, Robert A. Sikes
    Pages 181-203
  14. The Role of Allogeneic Bone Marrow Transplant in Cancer Treatment

    • Jose Francisco Tomas, Sergio A. Giralt
    Pages 229-239
  15. The Role of Radiosurgery in the Treatment of Bone Localized Cancers

    • Marsha Haley, Peter C. Gerszten, Steven A. Burton
    Pages 241-251
  16. Back Matter

    Pages 1-12

About this book

Bone and Cancer is the fifth volume in the series Topics in Bone Biology, edited by Felix Bronner and Mary C. Farach-Carson. This title features current knowledge on mechanisms of metastasis, the role of the bone microenvironment in cancer progression, how inflammatory cytokines function in metastasis and osteolysis, and the role of osteoblasts, thus bringing to the clinician and researcher cellular and molecular findings that affect the search for drugs and lead to translational studies.

Each chapter contains an extensive bibliography that permits readers to learn more about specific aspects of the chapter topic.  Tables, diagrams and figures illustrate and clarify cellular events that lead to development and progression of cancer in bone. Insights based on cellular and molecular events clarify the clinical picture and may lead to translational research and focused therapy.  The chapters, authored by authorities from throughout the world, emphasize how current knowledge can lead to better treatement.

Other titles in this series:-

Bone Formation

Bone Resorption

Engineering of Functional Skeletal Tissues

Bone and Osteoarthritis

Reviews

From the reviews:

“This book covers the basic science and translational and clinical aspects of bone cancer and bone tumors. … The target audience is clearly an elite group of clinicians and scientists who are focused on understanding future innovations in the treatment of bone related cancers. … a great addition to the lab that is studying bone cancers or for the clinician who is actively treating patients with bone cancer. … the average orthopedist will find in deeper scientifically than is necessary for a general orthopedic practice.” (Mark R. Hutchinson, Doody’s Review Service, December, 2009)

“This book is the fifth volume in the series Topics in Bone Biology. It presents up to date knowledge in the mechanisms of cancer in bone. … The book is well written, extensively referenced and comprehensive. It has been well edited, and chapters are of a consistent layout. … The book will make a good addition to a departmental library in any unit managing skeletal cancer.” (Robert U. Ashford, European Journal of Orthopaedic Surgery & Traumatology, Vol. 21, 2011)

Editors and Affiliations

  • University of Connecticut Health Center, Farmington, USA

    Felix Bronner

  • University of Delaware, Newark, USA

    Mary C. Farach-Carson

About the editors

Series Editors of Topics in Bone Biology are: Professors Felix Bronner, PhD - University of Connecticut Health Center, Farmington, CT, USA, and Dr Mary C. Farach-Carson, PhD - the Department of Biology, University of Delaware, Newark, DE, USA

Bibliographic Information

  • Book Title: Bone and Cancer

  • Editors: Felix Bronner, Mary C. Farach-Carson

  • Series Title: Topics in Bone Biology

  • DOI: https://doi.org/10.1007/978-1-84882-019-7

  • Publisher: Springer London

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag London 2009

  • Hardcover ISBN: 978-1-84882-018-0Due: 18 June 2009

  • eBook ISBN: 978-1-84882-019-7Published: 20 June 2009

  • Series ISSN: 2199-2436

  • Series E-ISSN: 2199-2444

  • Edition Number: 1

  • Number of Pages: X, 246

  • Number of Illustrations: 28 b/w illustrations, 35 illustrations in colour

  • Topics: Oncology, Orthopedics, Cancer Research

Buy it now

Buying options

eBook USD 229.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 299.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access