Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 1105)
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Table of contents (43 protocols)
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Front Matter
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Analysis of DNA Adducts
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Front Matter
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Detection of Chromosomal and Genome-Wide Damage
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Front Matter
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About this book
Molecular Toxicology Protocols, Second Edition aims to bring together a series of articles describing validated methods to elucidate specific molecular aspects of toxicology, the emphasis being on the application of molecular methods to genetic toxicology. The volume is divided into ten parts, roughly corresponding to the spectrum of biomarkers intermediate between exposure and disease outcomes as proposed in molecular epidemiology models. Subjects of these new chapters range from preparation of fluid specimens for analysis of cellular inflammatory responses to genotoxic insults to sensitive methods for proteomic analysis and aberrant DNA methylation patterns. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.
Authoritative and easily accessible, Molecular Toxicology Protocols, Second Edition addresses not only the needs of molecular biologists and toxicologists, but also those of individuals interested in applying molecular methods to clinical applications, such as geneticists, pathologists, biochemists, and epidemiologists.
Editors and Affiliations
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Occupational Health, University of Pittsburgh Dept. Environmental &, Pittsburgh, USA
Phouthone Keohavong
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Dept. of Pharmaceutical Sciences, Nova Southeastern University College of Pharmacy, Fort Lauderdale, USA
Stephen G. Grant
Bibliographic Information
Book Title: Molecular Toxicology Protocols
Editors: Phouthone Keohavong, Stephen G. Grant
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-62703-739-6
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2014
Hardcover ISBN: 978-1-62703-738-9Published: 13 March 2014
Softcover ISBN: 978-1-4939-5654-8Published: 03 September 2016
eBook ISBN: 978-1-62703-739-6Published: 12 March 2014
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 2
Number of Pages: XV, 646
Number of Illustrations: 72 b/w illustrations, 29 illustrations in colour
Topics: Pharmacology/Toxicology, Human Genetics