Overview
- Includes clear, reproducible techniques that are proven in the field
- Presents research on synaptic mechanisms of brain function as well as clinically-relevant strategies for preventing and alleviating neurological and psychiatric disorders
- Features tips and key implementation advice from experts
- Includes supplementary material: sn.pub/extras
Part of the book series: Neuromethods (NM, volume 81)
Access this book
Tax calculation will be finalised at checkout
Other ways to access
Table of contents (12 protocols)
-
Front Matter
-
Biochemical and Genetic Strategies for Probing Synaptic Plasticity and Behavior
-
Front Matter
-
-
Synaptic Development and Neurogenesis
-
Front Matter
-
-
Electrophysiological and Optical Interrogation of Synaptic Physiology in Brain Slices and Dissociated Cell Preparations
-
Front Matter
-
-
Back Matter
Keywords
About this book
Investigations involving incisive mechanistic dissection of various types of synaptic plasticity have revealed that it plays key roles in neural development, sensory information processing, cortical remapping following brain injury, perception, and behavioral learning and memory. Disruptions of synaptic plasticity may underlie neurological and behavioral disorders such as Alzheimer disease, Fragile-X syndrome, autism, and drug addiction. Multidisciplinary Tools for Investigating Synaptic Plasticity, therefore, assembles expert contributions that highlight techniques and strategies used in probing the cellular and molecular mechanisms of synaptic plasticity in the nervous systems of vertebrate and invertebrate species. Divided into three sections, this meticulous volume describes biochemical and genetic strategies for studying synaptic plasticity, behavior, neural development, and synaptogenesis, and also includes cellular electrophysiological and optical methods for interrogating a diverse array of mechanistic issues. As part of the Neuromethods series, this book contains the kind of detail and key implementation advice that maximizes successful results.
Authoritative and invaluable, Multidisciplinary Tools for Investigating Synaptic Plasticity serves as an ideal primer for introducing researchers to specific techniques that will enhance their success at addressing novel questions in synaptic plasticity at the lab bench.
Editors and Affiliations
Bibliographic Information
Book Title: Multidisciplinary Tools for Investigating Synaptic Plasticity
Editors: Peter Nguyen
Series Title: Neuromethods
DOI: https://doi.org/10.1007/978-1-62703-517-0
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2013
Hardcover ISBN: 978-1-62703-516-3Published: 10 July 2013
Softcover ISBN: 978-1-4939-5919-8Published: 23 August 2016
eBook ISBN: 978-1-62703-517-0Published: 10 July 2013
Series ISSN: 0893-2336
Series E-ISSN: 1940-6045
Edition Number: 1
Number of Pages: XIV, 274
Number of Illustrations: 28 b/w illustrations, 27 illustrations in colour
Topics: Neurosciences, Human Physiology, Neurochemistry