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  • © 2013

New Advances on Disease Biomarkers and Molecular Targets in Biomedicine

  • Covers important topics, such as identification of drug targets and disease biomarkers
  • Provides a foundation for further development and advancement in biomedical research
  • Summarizes current research and highlights future prospective with an aim to pave the path for new direction

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xii
  2. Nonreceptor Protein Kinases c-Src, c-Yes, and FAK Are Biomarkers for Male Contraceptive Research

    • Xiang Xiao, Dolores D. Mruk, Pranitha Jenardhanan, Jayakanthan Mannu, Premendu P. Mathur, Will M. Lee et al.
    Pages 1-25
  3. MicroRNA as Cancer Biomarkers and Targets

    • Kwong-Fai Wong, Xiaoou Jiang, John M. Luk
    Pages 39-56
  4. Oncofetal Molecules as Biomarkers and Drug Targets for Hepatic Cancer

    • Felix H. Shek, Tracy C. W. Lai, Sarwat Fatima, Nikki P. Lee
    Pages 57-74
  5. Ion Channels as Novel Pancreatic Cancer Biomarkers and Targets

    • Nelson S. Yee, Rosemary K. Yee
    Pages 75-84
  6. Circulating Biomarkers for Esophageal Squamous Cell Carcinoma

    • Kenneth K. Lai, Kin-Tak Chan, Sarwat Fatima, Nikki P. Lee, Simon Law
    Pages 85-103
  7. CARF Regulates Cellular Senescence and Apoptosis through p53-Dependent and -Independent Pathways

    • Renu Wadhwa, Rumani Singh, Zeenia Kaul, Sunil C. Kaul
    Pages 137-157
  8. Targeting Cancer Metabolisms

    • Angela M. Liu, Wei Wang, John M. Luk
    Pages 159-174
  9. Modulation of Autophagy as a Novel Cancer Therapeutic Strategy

    • Jianzhou Cui, Han-Ming Shen
    Pages 175-203
  10. Functional Proteomics Screening for Novel Anti-viral Drug Targets

    • Shengtao Zhou, Manchao Kuang, Xia Zhao, Canhua Huang
    Pages 205-216
  11. Mesoporous Silica Nanoparticles for Cancer Therapy

    • Qian Liu, Weiliang Xia
    Pages 231-242
  12. Chemoresistance in Glioma

    • Stella Sun, Derek Lee, Gilberto K. K. Leung
    Pages 243-270
  13. Back Matter

    Pages 271-275

About this book

Rising occurrences of various diseases and epidemics have pressurized the already-burdened health system across the globe, and this imposes an unprecedented challenge on our current research in identifying disease-specific biomarkers and molecular targets, in particular for cancers, neurological disorders and unexplained infertility. Despite decades of efforts in deciphering the fundamental biology underlying various diseases at discrete levels using an array of advanced technologies, attempts to identify reliable and disease-indicating markers for detection and biomolecules or cellular structures for targeting are still in vain. This monograph describes and discusses the updated findings in this field with a specific aim to compile prior and recent literature and from there to acquire some insights to facilitate future research to expand options of understanding, detecting and treating diseases. Among the many possible areas of biomedical research, this content comprises two themes: disease biomarkers and molecular targets. The book also covers topics that are more advanced in development to emerging scientific discoveries. In particular, this monograph includes concepts on the renovated use of oncofetal molecules in cancer prediction and treatment, the evolving development in cancer biology at the cellular and molecular levels and the recent involvement on new classes of molecules in diseases. This book renews established concepts in the field, and at the same time leads to important insights for research and development of drugs, diagnostics, and interventions for managing diseases of unmet medical needs.

Editors and Affiliations

  • Faculty of Medicine Building, Department of Surgery, University of Hong Kong, Hong Kong, Hong Kong SAR

    Nikki P. Lee

  • Center for Biomedical Research, Population Council, NEW YORK, USA

    C.Y. Cheng

  • Yong Loo Lin School of Medicine, Department of Pharmacology and Departmen, National University of Singapore, Singapore, Singapore

    John M. Luk

Bibliographic Information

  • Book Title: New Advances on Disease Biomarkers and Molecular Targets in Biomedicine

  • Editors: Nikki P. Lee, C.Y. Cheng, John M. Luk

  • DOI: https://doi.org/10.1007/978-1-62703-456-2

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media New York 2013

  • Hardcover ISBN: 978-1-62703-455-5Published: 22 June 2013

  • Softcover ISBN: 978-1-62703-901-7Published: 09 July 2015

  • eBook ISBN: 978-1-62703-456-2Published: 22 June 2013

  • Edition Number: 1

  • Number of Pages: XII, 275

  • Topics: Cell Biology, Cancer Research, Pharmacology/Toxicology

Buy it now

Buying options

eBook USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access