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  • © 2013

In Silico Systems Biology

  • Includes cutting-edge methods and protocols in the MiMB standard format
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 1021)

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Table of contents (16 protocols)

  1. Front Matter

    Pages i-x
  2. Visualization and Analysis of Biological Networks

    • Pablo Porras Millán
    Pages 63-88
  3. Modeling Signaling Networks with Different Formalisms: A Preview

    • Aidan MacNamara, David Henriques, Julio Saez-Rodriguez
    Pages 89-105
  4. From a Biological Hypothesis to the Construction of a Mathematical Model

    • David Cohen, Inna Kuperstein, Emmanuel Barillot, Andrei Zinovyev, Laurence Calzone
    Pages 107-125
  5. Practical Use of BiNoM: A Biological Network Manager Software

    • Eric Bonnet, Laurence Calzone, Daniel Rovera, Gautier Stoll, Emmanuel Barillot, Andrei Zinovyev
    Pages 127-146
  6. Using Chemical Kinetics to Model Biochemical Pathways

    • Nicolas Le Novère, Lukas Endler
    Pages 147-167
  7. Simulation of Stochastic Kinetic Models

    • Andrew Golightly, Colin S. Gillespie
    Pages 169-187
  8. BioModels Database: A Repository of Mathematical Models of Biological Processes

    • Vijayalakshmi Chelliah, Camille Laibe, Nicolas Le Novère
    Pages 189-199
  9. Supporting SBML as a Model Exchange Format in Software Applications

    • Sarah M. Keating, Nicolas Le Novère
    Pages 201-225
  10. Controlled Annotations for Systems Biology

    • Nick Juty, Camille Laibe, Nicolas Le Novère
    Pages 227-245
  11. Bayesian Approaches for Mechanistic Ion Channel Modeling

    • Ben Calderhead, Michael Epstein, Lucia Sivilotti, Mark Girolami
    Pages 247-272
  12. Uniform Curation Protocol of Metazoan Signaling Pathways to Predict Novel Signaling Components

    • Máté Pálfy, Illés J. Farkas, Tibor Vellai, Tamás Korcsmáros
    Pages 285-297
  13. Back Matter

    Pages 311-313

About this book

Systems biology can now be considered an established and fundamental field in life sciences. It has moved from the identification of molecular 'parts lists' for living organisms towards synthesising information from different 'omics'-based approaches to generate and test new hypotheses about how biological systems work. In In Silico Systems Biology: Methods and Protocols, expert researchers in the field detail a practical set of chapters based often on actual materials used and develop for face-to-face training with examples and case studies.  Written in the highly successful Methods in Molecular Biology  series format, chapters include introductions to their respective topics, step-by-step workflows, and key tips on troubleshooting and avoiding known pitfalls.

 Authoritative and practical, In Silico Systems Biology: Methods and Protocols seeks to aid scientists in the further study of network biology and mathematical models of biological systems.

Editors and Affiliations

  • The Genome Analysis Centre, Norwich, United Kingdom

    Maria Victoria Schneider

Bibliographic Information

  • Book Title: In Silico Systems Biology

  • Editors: Maria Victoria Schneider

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-62703-450-0

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2013

  • Hardcover ISBN: 978-1-62703-449-4Published: 29 May 2013

  • Softcover ISBN: 978-1-4939-6295-2Published: 23 August 2016

  • eBook ISBN: 978-1-62703-450-0Published: 29 May 2013

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: X, 313

  • Number of Illustrations: 18 b/w illustrations, 70 illustrations in colour

  • Topics: Bioinformatics

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access