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Chiral Separations

Methods and Protocols

  • Book
  • © 2013

Overview

  • Focuses on analytical seperation sciences by chromatographic and electrophoretic techniques
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 970)

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Table of contents (32 protocols)

Keywords

About this book

 There is a demand for analytical methods that are able to discriminate between enantiomers in order to analyze the enantiomeric purity of compounds from natural or chemical sources not only in pharmaceutical sciences but in any field on bioactive compounds including chemistry, biology, biochemistry, forensic, and environmental sciences and many others. The second edition of Chiral Separations: Methods and Protocols, expands upon the previous edition with current methodology, providing an overview and especially practically oriented applications of the most important analytical techniques in chiral separation sciences. New chapters on analytical separation sciences by chromatographic and electrophoretic techniques have been added as has simulated moving bed chromatography as a preparative method. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and cutting-edge, Chiral Separations: Methods and Protocols, Second Edition is helpful for analytical chemists working on stereochemical problems in fields or pharmacy, chemistry, biochemistry, food chemistry, molecular biology, forensics, environmental sciences or cosmetics in academia, government or industry.

Reviews

From the reviews of the second edition:

“The second edition of Chiral Separations: Methods and Protocols discusses almost every kind of chiral separation method, with the emphasis on fundamental research and experimental design. … it is a very useful book for scientists and students involved in the enantioseparation field, and scientists involved in R & D areas such as drug development and environmental monitoring can also benefit from this monograph. It is expected that this book will definitely promote research in chirality-related fields.” (Huwei Liu, Analytical and Bioanalytical Chemistry, Vol. 406, 2014)

“The book provides an overview and practically oriented applications of the most important analytical techniques in chiral separations. … the chapters include introductions, lists of necessary materials and reagents, step-by-step laboratory protocols, and troubleshooting tips. Pharmacists, biochemists, chemists, food chemists, molecular biologists, and forensic and environmental scientists will find this book extremely useful.” (Omer Iqbal, Doody’s Book Reviews, August, 2013)

Editors and Affiliations

  • , Department of Pharmaceutical Chemistry, Friedrich-Schiller-University Jena, Jena, Germany

    Gerhard K. E. Scriba

Bibliographic Information

  • Book Title: Chiral Separations

  • Book Subtitle: Methods and Protocols

  • Editors: Gerhard K. E. Scriba

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-62703-263-6

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2013

  • Hardcover ISBN: 978-1-62703-262-9Published: 03 January 2013

  • Softcover ISBN: 978-1-4939-5974-7Published: 23 August 2016

  • eBook ISBN: 978-1-62703-263-6Published: 04 January 2013

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 2

  • Number of Pages: XVII, 531

  • Topics: Biochemistry, general, Chromatography

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