Editors:
- Presents a comprehensive overview of the biophysical and biochemical properties of the titular probes
- Features easy and accessible descriptions of the main imaging tools and methods now available
- Includes detailed protocols based on the most cutting-edge biological advances
Part of the book series: Neuromethods (NM, volume 72)
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Table of contents (9 protocols)
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Front Matter
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Back Matter
About this book
In the last decade, several different optical imaging techniques, either based on various voltage or calcium dyes, or more recently on modified fluorescent or bioluminescent proteins (genetically encoded) that are sensitive to calcium, have been developed to study neuronal activity, and especially groups of neurons, with the goal of mapping and deciphering the neural code underlying major neurophysiological functions. Genetically Encoded Functional Indicators brings together expert contributors to present the development of recent genetic techniques that allow for generating genetically encoded activity sensors in order to investigate neuronal activity. Each chapter describes a specific sensor and its utilization to study neuronal activity in a particular way. Written in the Neuromethods series style, chapters contain the kind of key description and implementation advice that guarantees successful results.
Helpful and easy to use, Genetically Encoded Functional Indicators aims to inspire students and researchers and to serve as a useful guide to those who wish to start using these different brain imaging techniques and require a bit of guidance in how best to choose a technique to match the goal of their study.
Editors and Affiliations
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ICFC, Neurobiologie & Developpement, CNRS, UPR-3294, Gif-sur-Yvette, France
Jean-René Martin
Bibliographic Information
Book Title: Genetically Encoded Functional Indicators
Editors: Jean-René Martin
Series Title: Neuromethods
DOI: https://doi.org/10.1007/978-1-62703-014-4
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2012
Hardcover ISBN: 978-1-62703-013-7Published: 01 August 2012
Softcover ISBN: 978-1-4939-5938-9Published: 23 August 2016
eBook ISBN: 978-1-62703-014-4Published: 01 August 2012
Series ISSN: 0893-2336
Series E-ISSN: 1940-6045
Edition Number: 1
Number of Pages: XII, 169
Topics: Neurosciences, Human Genetics, Neurology