Overview
- Editors:
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Maria Kavallaris
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Australia for Medical Research, Iron Metabolism Program, Children's Cancer Institute, Randwick, Australia
- Comprehensive in scope
- Written by experts
- With numerous illustrations
- Includes supplementary material: sn.pub/extras
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Table of contents (20 chapters)
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Basics of the Cytoskeleton
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- Vera Dugina, Richard Arnoldi, Paul A. Janmey, Christine Chaponnier
Pages 3-28
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- Pavel Dráber, Eduarda Dráberová
Pages 29-53
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- Omar A. Quintero, Judy E. Moore, Christopher M. Yengo
Pages 73-100
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Actin and Disease
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Front Matter
Pages 101-101
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- Rhea Cornely, Thomas Grewal, Katharina Gaus
Pages 103-121
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- Anthony J. Kee, Edna C. Hardeman
Pages 123-140
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- Stephen P. Robertson, Philip B. Daniel
Pages 141-158
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- Alice Schofield, Ora Bernard
Pages 159-168
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- MatÃas MorÃn, Fernando Mayo, Felipe Moreno, Miguel A. Moreno-Pelayo
Pages 169-180
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- Teresa Bonello, Jason Coombes, Galina Schevzov, Peter Gunning, Justine Stehn
Pages 181-200
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Microtubules and Disease
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Front Matter
Pages 201-201
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- April L. Risinger, Susan L. Mooberry
Pages 203-221
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- Joshua A. McCarroll, Maria Kavallaris
Pages 223-240
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- Suzan K. Chao, Chia-Ping H. Yang, Susan Band Horwitz
Pages 241-257
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- Dominic Chi Hiung Ng, Frances Byrne
Pages 259-284
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- Xavier H. Jaglin, Jamel Chelly, Nadia Bahi-Buisson
Pages 315-341
About this book
The cytoskeleton is comprised of a variety of specialized proteins, and is a dynamic structure that is involved in the majority of key cellular events. There is increasing interest in the role of the cytoskeleton in human disease. This volume brings together human disease states where cytoskeletal disruptions are driving disease. Our emerging understanding of the molecular and cellular events that drive cytoskeletal mediated diseases including cancer, heart disease, myopathies and skin disorders, are also helping shape targeted therapeutic approaches to treating these diseases.
Editors and Affiliations
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Australia for Medical Research, Iron Metabolism Program, Children's Cancer Institute, Randwick, Australia
Maria Kavallaris
About the editor
Maria Kavallaris, Ph.D. is Head of the Tumour Biology and Targeting Program and a National Health and Medical Research Council Senior Research Fellow at the Children's Cancer Institute Australia. She also holds appointments as Director of the Australian Centre for Nanomedicine and Professor at the University of New South Wales. Maria has made fundamental contributions in identifying mechanisms of action and resistance to anticancer drugs that target tubulin and discovering new cytoskeleton interactions in cell division and tumor formation. She obtained her Ph.D. from the University of New South Wales and undertook her postdoctoral studies as an International Agency for Cancer Research Fellow at the Albert Einstein College of Medicine, New York. She has served on numerous grant review panels, scientific advisory committees, pharmaceutical advisory boards and is a past President of the Australian Society for Medical Research. Maria is a Director of the Australian Institute for Policy and Science.
