Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 851)
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Table of contents (21 protocols)
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Front Matter
Keywords
About this book
The advancements of medical technology, improvements in medical care, and increased patients’ life span make pain research and related drug development high priorities for both the research community and pharmaceutical companies. Rapid development of basic science research tools, such as techniques of flurometric labeling, genomic and proteomic high throughput screening, and genetically modified animals, promotes the swift acceleration of pain research to a stage allowing integrated investigations of pain processing mechanisms at the single cell and/or molecule level, and in a spatially and temporally controlled manner. Using multidisciplinary approaches, we can dissect the complicity of the sensory circuits connecting peripheral stimulation to maladaptive changes in the sensory pathways as well as pain perceptions at the central nervous system. Pain Research: Methods and Protocols, Second Edition provides advanced techniques and animal models that are critical for integrated pain research. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.
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Authoritative and accessible, Pain Research: Methods and Protocols, Second Edition serves as an ideal guide to novice pain researchers who may not have extensive experiences in the field, or to experienced pain researchers who would like to expand their research in new directions and/or to new mechanisms in different models.Â
Reviews
From the reviews of the second edition:
“This second edition of Pain Research – Methods and Protocols is an excellent compendium of chapters outlining the most current techniques used to study the neurobiology of pain. … Pain Research – Methods and Protocols is aimed not only at the novice researcher with little experience in the field but also at bringing new techniques and approaches to the pain research community as a whole. The clear organizational structure of the text makes this a highly achievable goal.” (Bradley Kerr, Canadian Journal of Anesthesia/Journal Canadien d'anesthésie, Vol. 60, January, 2013)Editors and Affiliations
Bibliographic Information
Book Title: Pain Research
Book Subtitle: Methods and Protocols
Editors: Z. David Luo
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-61779-561-9
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2012
Hardcover ISBN: 978-1-61779-560-2Published: 16 February 2012
Softcover ISBN: 978-1-4939-6095-8Published: 23 August 2016
eBook ISBN: 978-1-61779-561-9Published: 16 February 2012
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 2
Number of Pages: XI, 287
Number of Illustrations: 63 b/w illustrations, 3 illustrations in colour
Topics: Molecular Medicine, Pain Medicine