Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 756)
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Table of contents (25 protocols)
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Front Matter
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Overviews
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Front Matter
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Receptor–Ligand Interactions
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Front Matter
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Receptor–Receptor Interactions
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Front Matter
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Receptor–Effector Coupling
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Front Matter
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About this book
It is increasingly clear that signal transduction is a highly organized and integrated process. Divided into two convenient sections, Signal Transduction Protocols, Third Edition focuses on experimental approaches to better understand the complexity of signal transduction. Introductory chapters provide perspective on several of the challenges involved in signal transduction research and offer guidance on selecting the best approaches to various types of questions. The individual chapters provide detailed experimental protocols covering various topics, from the effects of ligand binding on receptor conformation and effector coupling, to moving inside the cell in order to capture the spatial and temporal characteristics of signaling events. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.
Authoritative and accessible, Signal Transduction Protocols serves as an ideal guide to scientists of all backgrounds and is a valuable resource for future progress in the field of signal transduction research.
Reviews
From the reviews of the third edition:
“This well-illustrated book on signal transduction protocols is a valuable resource for scientists interested in learning the intricate details of complex signaling events that take place within the cell … . Although written for the scientists in the field of signal transduction research, it also will be useful for graduate students and other investigators in pharmacology interested in this area. … Given the rapid advances in the field of signal transduction, this third edition is essential.” (Omer Iqbal, Doody’s Book Reviews, March, 2012)Editors and Affiliations
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Div. Endocrinology, Metabolism &, Medical Genetics, Medical University of South Carolina, Charleston, USA
Louis M. Luttrell
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Dept. Physiology & Pharmacology, University of Western Ontario, London, Canada
Stephen S. G. Ferguson
Bibliographic Information
Book Title: Signal Transduction Protocols
Editors: Louis M. Luttrell, Stephen S. G. Ferguson
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-61779-160-4
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2011
Hardcover ISBN: 978-1-61779-159-8Published: 30 August 2011
Softcover ISBN: 978-1-4939-6108-5Published: 23 August 2016
eBook ISBN: 978-1-61779-160-4Published: 27 August 2011
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 3
Number of Pages: XIV, 430
Topics: Cell Biology, Protein-Ligand Interactions