Overview
- Features cutting-edge protocols from this expanding and celebrated field of study
- Details biochemical, molecular, and proteomic approaches
- Contains expert tips and key implementation advice
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 735)
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Table of contents (17 protocols)
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Front Matter
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Back Matter
Keywords
About this book
New and rapid advances in technology have equipped us with a variety of tools and platforms to ask fundamental questions of telomere regulation and have allowed investigators to carry out experiments using diverse model systems. For example, proteomic, genomic, and molecular approaches have afforded us unprecedented insight into the complex protein interaction networks at work on the telomere chromatin and the detailed information regarding telomere dynamics in response to stress or stimuli. Telomeres and Telomerase: Methods and Protocols, Second Edition builds upon the telomerase assays featured in the popular first edition to encompass many different assays that allow investigators to query the function of telomere proteins and the responses of the telomere DNA, including detailed examinations of biochemical, molecular, and proteomic approaches. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and expert tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Telomeres and Telomerase: Methods and Protocols, Second Edition serves as an ideal, up-to-date guide for investigators further pursing this vital field of study.
Reviews
From the reviews of the second edition:
“The book provides different assays to study the function of telomere proteins and the responses of the telomere DNA. It also provides protocols for biochemical, molecular, and proteomic approaches in the understanding of telomere dynamics. It appears to be intended for investigators interested in the field of telomere and telomerase, but it also will be of immense help to other clinicians interested in cell growth, proliferation, aging, and cancer.” (Omer Iqbal, Doody’s Book Reviews, February, 2012)Editors and Affiliations
Bibliographic Information
Book Title: Telomeres and Telomerase
Book Subtitle: Methods and Protocols
Editors: Zhou Songyang
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-61779-092-8
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2011
Hardcover ISBN: 978-1-61779-091-1Published: 12 April 2011
Softcover ISBN: 978-1-4939-5627-2Published: 23 August 2016
eBook ISBN: 978-1-61779-092-8Published: 02 April 2011
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 2
Number of Pages: X, 191
Topics: Biochemistry, general