Editors:
- Contains comprehensive and extensive practical coverage of polyamine-related methodologies in a wide variety of subject areas
- Features step-by-step protocols, clearly written and readily reproducible
- Includes expert tips and key implementation advice to ensure methodological success
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 720)
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Table of contents (33 protocols)
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Front Matter
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Introduction
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Front Matter
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Identification of Polyamine Metabolic Enzymes and Characterization of Polyamine-Regulated Genes and Ion Channels
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Front Matter
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Transgenic Models for Study of Polyamine Function
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Front Matter
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Enzymes Involved in Polyamine Catabolism and Posttranslational Protein Modification
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Front Matter
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Enzymes Involved in Polyamine Catabolism and Post-Translational Protein Modification
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Regulation of Polyamine Content
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Front Matter
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About this book
Recently, important new findings in the polyamine field and a variety of new experimental systems have revolutionized the study of these ubiquitous cellular components, essential for normal growth and development. In Polyamines: Methods and Protocols, leading researchers contribute an extensive collection of up-to-date laboratory techniques for the further pursuit of polyamine study. The volume delves into vital subjects such as neoplasia studies with animal models and human patients, therapeutic roles for polyamine inhibitors and analogs, polyamine metabolism and oxidative damage, polyamines as regulators of critical ion channels, as well as polyamine transport systems and polyamine-responsive genes. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and expert notes on troubleshooting and avoiding known pitfalls.
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Comprehensive and cutting-edge, Polyamines: Methods and Protocols provides a key resource for all scientists pursuing the study of this dynamic and significant aspect of cellular biology.Editors and Affiliations
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College of Medicine, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey, USA
Anthony E. Pegg
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School of Medicine, Sidney Kimmel Comprehensive, Johns Hopkins University, Baltimore, USA
Robert A. Casero, Jr.
Bibliographic Information
Book Title: Polyamines
Book Subtitle: Methods and Protocols
Editors: Anthony E. Pegg, Robert A. Casero, Jr.
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-61779-034-8
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2011
Hardcover ISBN: 978-1-61779-033-1Published: 21 February 2011
Softcover ISBN: 978-1-4939-5839-9Published: 23 August 2016
eBook ISBN: 978-1-61779-034-8Published: 14 February 2011
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIV, 523
Topics: Cell Biology, Laboratory Medicine