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  • © 2011

Intraoperative Irradiation

Techniques and Results

  • Details IORT indications, techniques, and results.
  • Covers issues of basic science and physics.
  • Provides a more balanced presentation of techniques and results by disease-site.
  • Multi-national and multi-disciplinary authorship including both radiation oncologists and surgeons.
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Clinical Oncology (CCO)

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-xvii
  2. General Rationale and Historical Perspective

    1. Front Matter

      Pages 1-1
    2. Rationale and Historical Perspective of Intraoperative Irradiation

      • Leonard L. Gunderson, Felipe A. Calvo, Christopher G. Willett, Louis B. Harrison
      Pages 3-26
    3. Biology of Large Dose per Fraction Irradiation

      • Paul Okunieff, Srinath Sundararaman, Su Metcalfe, Yuhchyau Chen
      Pages 27-47
  3. Methods and Techniques of Treatment

    1. Front Matter

      Pages 49-49
  4. Methods and Techniques of Treatment

    1. Intraoperative Electron Beam Irradiation: Physics and Techniques

      • Peter Biggs, Christopher G. Willett, Harm Rutten, Mario Ciocca, Leonard L. Gunderson, Felipe A. Calvo
      Pages 51-72
    2. HDR-IORT: Physics and Techniques

      • Eli E. Furhang, Jussi K. Sillanpaa, Kenneth S. Hu, Louis B. Harrison
      Pages 73-84
    3. Electronic Brachytherapy/Low KV-IORT: Physics and Techniques

      • Uta Kraus-Tiefenbacher, Peter Biggs, Jayant Vaidya, Dario Francescatti
      Pages 85-98
    4. IORT with Electron-Beam, High-Dose-Rate Brachytherapy or Low-KV/Electronic Brachytherapy: Methodological Comparisons

      • Subir Nag, Christopher G. Willett, Leonard L. Gunderson, Louis B. Harrison, Felipe A. Calvo, Peter Biggs
      Pages 99-115
  5. Normal Tissue Tolerance: IORT

    1. Front Matter

      Pages 117-117
  6. Normal Tissue Tolerance – IORT

    1. Normal-Tissue Tolerance to IOERT, EBRT, or Both: Animal and Clinical Studies

      • Zeljko Vujaskovic, Christopher G. Willett, Joel E. Tepper, Timothy J. Kinsella, Leonard L. Gunderson
      Pages 119-138
  7. Results of IORT Alone or Plus EBRT by Disease Site

    1. Front Matter

      Pages 139-139
  8. Results of IORT alone or plus EBRT by Disease Site

    1. Central Nervous System Tumors

      • David Ortiz de Urbina, Patrick Schueller, Normann Willich, Kintomo Takakura, Osami Kubo, Felipe A. Calvo
      Pages 141-161
    2. Head and Neck Cancer

      • Kenneth S. Hu, Sue Yom, Michael J. Kaplan, Rafael Martinez-Monge, Louis B. Harrison
      Pages 163-188
    3. Breast Cancer

      • Felix Sedlmayer, Jean-Bernard DuBois, Roland Reitsamer, Gerd Fastner, David Olilla, Roberto Orecchia
      Pages 189-200
    4. Lung Cancer

      • Javier Aristu, Felipe A. Calvo, Marta Moreno, Rafael Martínez, Jesús Herreros, María Esperanza Rodriguez et al.
      Pages 201-222
    5. Gastric Cancer

      • Rafael Martinez-Monge, Miren Gaztañaga, Javier Álvarez-Cienfuegos, Robert C. Miller, Felipe A. Calvo
      Pages 223-248
    6. Pancreas Cancer

      • Robert C. Miller, Vincenzo Valentini, Adyr Moss, Giuseppe R. D’Agostino, Matthew D. Callister, Theodore S. Hong et al.
      Pages 249-271
    7. Bile Duct and Gallbladder Cancer

      • Takeshi Todoroki, Gernot M. Kaiser, Wolfgang Sauerwein, Leonard L. Gunderson
      Pages 273-295
    8. Primary Colorectal Cancer

      • Nils D. Arvold, Theodore S. Hong, Christopher G. Willett, Paul C. Shellito, Michael G. Haddock, Harm Rutten et al.
      Pages 297-322

About this book

The rationale for using intraoperative irradiation (IORT) is based on the realization that tolerable doses of eternal beam radiation are often insufficient to achieve control of locally advanced malignancies. In these instances, the IORT component of treatment becomes the optimal conformal technique of irradiation, since dose-limiting organs or structures can either be surgically displaced or protected by placement of lead shielding.

This fully revised and expanded second edition is of interest to those with intraoperative electron (IOERT) capabilities, high-dose-rate brachytherapy (HDR-IORT) capabilities, or both. Techniques, indications, and results are discussed by disease site. Each chapter is dual authored by a radiation oncologist and a surgeon, giving a balanced presentation of clinical scenarios. Issues of basic science and physics are also covered, and a notable chapter on normal tissue tolerance is included.

Intraoperative Irradiation: Techniques and Results, Second Edition is a superb compilation, providing essential cutting-edge knowledge. It is a foundation for physicians as IORT develops and becomes more widely available.

Editors and Affiliations

  • Department of Radiation Oncology, Mayo Clinic, Scottsdale, USA

    Leonard L. Gunderson

  • Dept. Radiation Oncology, Duke University Medical Center, Durham, USA

    Christopher G. Willett

  • Gregorio Marañón, Depto. Radiación de Oncología, Hospital General Universitario, Madrid, Spain

    Felipe A. Calvo

  • Albert Einstein College of Medicine, Radiation Oncology, Beth Israel Medical Center, New York, USA

    Louis B. Harrison

Bibliographic Information

  • Book Title: Intraoperative Irradiation

  • Book Subtitle: Techniques and Results

  • Editors: Leonard L. Gunderson, Christopher G. Willett, Felipe A. Calvo, Louis B. Harrison

  • Series Title: Current Clinical Oncology

  • DOI: https://doi.org/10.1007/978-1-61779-015-7

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2011

  • Hardcover ISBN: 978-1-61779-014-0Published: 15 April 2011

  • Softcover ISBN: 978-1-4939-6089-7Published: 23 August 2016

  • eBook ISBN: 978-1-61779-015-7Published: 15 April 2011

  • Series ISSN: 2364-1134

  • Series E-ISSN: 2364-1142

  • Edition Number: 2

  • Number of Pages: XVII, 529

  • Topics: Oncology

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access