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The Opiate Receptors

  • Book
  • © 2011

Overview

Editors:
  1. Gavril W. Pasternak

    1. , Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, USA

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  • 1. Fully revised and expanded, The Opiate Receptors, 2nd edition presents all the advances made in the field in the past twenty years
  • Covers a wide variety of topics relating to opioid drugs and mu receptors, delta receptors, and kappa opioid receptors
  • 3. Written by leading international researchers in the field, this new edition is as groundbreaking and vital as its predecessor
  • Includes supplementary material: sn.pub/extras

Part of the book series: The Receptors (REC)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xii
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  2. You’ve Come a Long Way Baby!

    • Solomon H. Snyder
    Pages 1-6

  3. The Evolution of Concepts

    • W. R. Martin
    Pages 7-21

  4. Pharmacology of Opioid Drugs

    • Brian M. Cox
    Pages 23-57

  5. Opioid Receptors: The Early Years

    • Gavril W. Pasternak
    Pages 59-91

  6. Endogenous Opioids

    • Iryna Berezniuk, Lloyd D. Fricker
    Pages 93-120

  7. Molecular Biology of Mu Opioid Receptors

    • Ying-Xian Pan, Gavril W. Pasternak
    Pages 121-160

  8. Delta Opioid Receptors

    • Wendy Walwyn, Fatima Macho Sánchez-Simon, Raquel Rodriguez, Christopher J. Evans
    Pages 161-179

  9. Kappa Opioid Receptor Gene and the Regulatory Mechanisms of Its Protein Expression

    • Li-Na Wei, Horace H. Loh
    Pages 181-194

  10. Opioid Receptor Signal Transduction Mechanisms

    • Ping-Yee Law
    Pages 195-238

  11. Mu Opioid Receptor Mediated Analgesia and Reward

    • Howard L. Fields
    Pages 239-264

  12. Kappa Opioid Receptor Function

    • Julia C. Lemos, Charles Chavkin
    Pages 265-305

  13. Delta Opioid Receptor Function

    • Edita Navratilova, Victor J. Hruby, Frank Porreca
    Pages 307-339

  14. Genetic Studies of Opioid System Function in Mice

    • Michael A. Ansonoff, Ting Wen, John E. Pintar
    Pages 341-388

  15. Opioid Receptor Trafficking

    • Mark von Zastrow
    Pages 389-405

  16. Opioid Receptor Dimerization

    • Raphael Rozenfeld, Ivone Gomes, Lakshmi A. Devi
    Pages 407-437

  17. Molecular Modulation of In Vivo Tolerance

    • Charles E. Inturrisi, Ann M. Gregus
    Pages 439-455

  18. Genetics of Opioid Actions

    • Jörn Lötsch, Jeffrey S. Mogil
    Pages 457-497

  19. Back Matter

    Pages 499-516
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About this book

This new edition covers the latest knowledge on opiate receptors and related receptor subtypes. It discusses many topics pertaining to the unique integrated approach of correlating the biochemical, physiological and pharmacological aspects of opiate reaction.

Reviews

From the reviews of the second edition:

“It is intended as a review and reference resource on topics of interest to scientists working in the opioid receptor field. … would be most appropriate for midlevel graduate students and higher level researchers … . The book offers a detailed overview and review of 14 different aspects of opioid receptor science … . an excellent source for a graduate level course on opioid pharmacology, or would serve well as a current reference point on timely issues in this field of research.” (Kenneth E. McCarson, Doody’s Review Service, June, 2011)

“The major goal of this second edition of The Opiate Receptors is to provide insight into the molecular and classical pharmacology of opiates and opioid peptides and to translate this into pharmacological actions. Gavril Pasternak … does a masterful job of bringing all of this together. … This book will be a valuable resource for scientists working in the opiate field and for clinicians who are interested in the pharmacological actions of these agents.” (Dwight Moulin, Canadian Journal of Neurological Sciences, March, 2012)

Editors and Affiliations

  • , Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, USA

    Gavril W. Pasternak

About the editor

In 1988, Gavril W. Pasternak published the first edition of The Opiate Receptors. Dr. Pasternak is affiliated with the Molecular Pharmacology & Chemistry department at the Sloan-Kettering Institute (Memorial Sloan-Kettering Cancer Center).

Bibliographic Information

  • Book Title: The Opiate Receptors

  • Editors: Gavril W. Pasternak

  • Series Title: The Receptors

  • DOI: https://doi.org/10.1007/978-1-60761-993-2

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2011

  • Hardcover ISBN: 978-1-60761-992-5Published: 02 December 2010

  • Softcover ISBN: 978-1-61779-721-7Published: 25 January 2013

  • eBook ISBN: 978-1-60761-993-2Published: 30 November 2010

  • Series ISSN: 1048-6909

  • Series E-ISSN: 2524-6488

  • Edition Number: 2

  • Number of Pages: XII, 516

  • Topics: Neurosciences

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