Skip to main content
SpringerLink
Log in
Book cover

Suppression and Regulation of Immune Responses

Methods and Protocols

  • Book
  • © 2011

Overview

Editors:
  1. Maria Cristina Cuturi

    1. CHUHotel Dieu, INSERM UMR 643, Nantes, France

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Ignacio Anegon

    1. CHU Hotel Dieu, INSERM UMR 643, Nantes, France

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Features the most recent advances in the field of immunoregulation with detailed but accessible chapters
  • Contains many step-by-step, laboratory protocols complete with lists of materials and vital notes from the experts
  • Includes chapters on physiological situations where immunoregulation play a central role, as in pregnancy
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 677)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 159.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (29 protocols)

  1. Front Matter

    Pages i-xviii
    Download chapter PDF

  2. Regulatory Cells

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Natural and Induced T CD4+CD25+FOXP3+ Regulatory T Cells

      • Lucienne Chatenoud
      Pages 3-13

    3. Polyclonal Expansion of Human CD4+CD25+ Regulatory T Cells

      • Petra Hoffmann, Ruediger Eder, Matthias Edinger
      Pages 15-30

    4. Methods for In Vitro Generation of Human Type 1 Regulatory T Cells

      • Silvia Gregori, Maria Grazia Roncarolo, Rosa Bacchetta
      Pages 31-46

    5. Ex Vivo Generation of Regulatory T Cells: Characterization and Therapeutic Evaluation in a Model of Chronic Colitis

      • Fridrik Karlsson, Sherry A. Robinson-Jackson, Laura Gray, Songlin Zhang, Matthew B. Grisham
      Pages 47-61

    6. Phenotypic and Functional Characterization of CD8+ T Regulatory Cells

      • Séverine Ménoret, Carole Guillonneau, Séverine Bezié, Lise Caron, Ignacio Anegon, Xian-Liang Li
      Pages 63-83

    7. Regulatory CD4– CD8– Double Negative T Cells

      • Edward Y. Kim, Stephen C. Juvet, Li Zhang
      Pages 85-98

    8. Identifying Regulatory B Cells (B10 Cells) that Produce IL-10 in Mice

      • Takashi Matsushita, Thomas F. Tedder
      Pages 99-111

    9. DCs in Immune Tolerance in Steady-State Conditions

      • Tomohiro Fukaya, Hideaki Takagi, Honami Taya, Katsuaki Sato
      Pages 113-126

    10. Plasmacytoid Dendritic Cells in Tolerance

      • Eric Gehrie, William Van der Touw, Jonathan S. Bromberg, Jordi C. Ochando
      Pages 127-147

    11. In Vitro-Generated DC with Tolerogenic Functions: Perspectives for In Vivo Cellular Therapy

      • Cees van Kooten, Kyra A. Gelderman
      Pages 149-159

    12. Preparation of Mouse Bone Marrow-Derived Dendritic Cells with Immunoregulatory Properties

      • Mercedes Segovia, Maria Cristina Cuturi, Marcelo Hill
      Pages 161-168

    13. Myeloid-Derived Suppressor Cells: Characterization and Expansion in Models of Endotoxemia and Transplantation

      • Nicolas Van Rompaey, Alain Le Moine
      Pages 169-180

    14. Human Regulatory Macrophages

      • James A. Hutchinson, Paloma Riquelme, Edward K. Geissler, Fred Fändrich
      Pages 181-192

    15. NKT and Tolerance

      • Julien Diana, Lucie Beaudoin, Anne-Sophie Gautron, Agnès Lehuen
      Pages 193-206

    16. Antiinflammatory and Immunosuppressive Functions of Mast Cells

      • Janet Kalesnikoff, Stephen J. Galli
      Pages 207-220

    17. A Mesenchymal Stem Cell Potency Assay

      • Joy Jiao, Jack M. Milwid, Martin L. Yarmush, Biju Parekkadan
      Pages 221-231

    18. In Vitro Analyses of the Immunosuppressive Properties of Neural Stem/Progenitor Cells Using Anti-CD3/CD28-Activated T Cells

      • Virginie Bonnamain, Isabelle Neveu, Philippe Naveilhan
      Pages 233-243

  3. Regulatory Molecules

    1. Front Matter

      Pages 245-245
      Download chapter PDF
Back to top

Keywords

About this book

Over the past several years, a high diversity of regulatory cells and suppressive molecules has taken centre stage in the field of immunoregulation. In Suppression and Regulation of Immune Responses: Methods and Protocols, expert researchers highlight recent advances in the identification, characterization, and generation of regulatory cells not only of the T cell lineage but also of other origins such as B, NK, myeloid, and dendritic cells, as well as the role of several suppressive molecules in immunoregulation. Particular emphasis is placed on the characterization of the molecular mechanisms and the therapeutic applications of regulatory cells and molecules in human diseases. Written as a volume in the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Comprehensive and cutting-edge, Suppression and Regulation of Immune Responses: Methods and Protocols serves as a key reference for scientists seeking a way toward greater control over the enormous power of the complex and vital immune system.

Reviews

From the reviews:

“This is a highly informative book, packed with a wealth of information covering all aspects of immune suppression and regulatory mechanisms. There is a diverse array of protocols offered, which are generally clear and easy to follow. … the wealth of information and literature reviews included make this book worth purchasing for those working in this field.” (Andrew Vaughan, Immunology News, August, 2011)

Editors and Affiliations

  • CHUHotel Dieu, INSERM UMR 643, Nantes, France

    Maria Cristina Cuturi

  • CHU Hotel Dieu, INSERM UMR 643, Nantes, France

    Ignacio Anegon

Bibliographic Information

  • Book Title: Suppression and Regulation of Immune Responses

  • Book Subtitle: Methods and Protocols

  • Editors: Maria Cristina Cuturi, Ignacio Anegon

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-60761-869-0

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2011

  • Hardcover ISBN: 978-1-60761-868-3Published: 13 October 2010

  • Softcover ISBN: 978-1-4939-6163-4Published: 23 August 2016

  • eBook ISBN: 978-1-60761-869-0Published: 13 October 2010

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XVIII, 473

  • Topics: Immunology

Publish with us

Policies and ethics

Back to top

Search

Navigation