Editors:
- Provides the most comprehensive reference volume describing current preclinical and clinical applications and protocols for photodynamic therapy (PDT)
- Covers state-of-the-art dosimetric procedures for measuring PDT doses and responses
- Details the step-by-step procedures required for accurately documenting cell death pathways following PDT mediated oxidative stress
- Includes extensive protocols for the emerging use of PDT to treat microbial infections
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 635)
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Table of contents (18 protocols)
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Front Matter
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Back Matter
About this book
Biological interactions of visible light with photosensitizers have been studied for over a century while controlled clinical applications of light and photosensitizers to treat solid tumors, known as photodynamic therapy, have been evolving since the mid 1970’s. In Photodynamic Therapy: Methods and Protocols, leading PDT scientists and clinicians provide the first comprehensive collection of methods and protocols specifically related to relevant mechanistic, dosimetric, preclinical, and clinical procedures used in current PDT research. Reflecting the growing number of studies demonstrating that immunological, tumor microenvironmental, and vascular responses are all contributing to PDT treatment outcomes, the contents of this volume move beyond the more traditional PDT concepts in order to investigate the numerous signal transduction and cell death pathways involved. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes which highlight tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Photodynamic Therapy: Methods and Protocols is an ideal guide for new investigators just starting out in PDT research as well as seasoned investigators changing the direction of their research with the intention of exploring this vital field of study.
Editors and Affiliations
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Keck School of Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, USA
Charles J. Gomer
Bibliographic Information
Book Title: Photodynamic Therapy
Book Subtitle: Methods and Protocols
Editors: Charles J. Gomer
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-60761-697-9
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2010
Hardcover ISBN: 978-1-60761-696-2Published: 06 May 2010
Softcover ISBN: 978-1-4939-5730-9Published: 23 August 2016
eBook ISBN: 978-1-60761-697-9Published: 16 June 2010
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 296
Topics: Molecular Medicine, Pathology