Anaphylaxis and Hypersensitivity Reactions

1. Front Matter

   Pages i-xiii

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2. Definition and Criteria for the Diagnoses of Anaphylaxis

   • Phil Lieberman

   Pages 1-12

3. An Epidemiological Approach to Reducing the Risk of Fatal Anaphylaxis

   • Richard S. H. Pumphrey

   Pages 13-31

4. Pathophysiology and Organ Damage in Anaphylaxis

   • Stephen F. Kemp, Richard F. Lockey

   Pages 33-46

5. Mast Cells: Effector Cells of Anaphylaxis

   • Mindy Tsai, Stephen J. Galli

   Pages 47-68

6. Basophils in Anaphylaxis

   • David E. Sloane, Donald MacGlashan

   Pages 69-87

7. Protease Mediators of Anaphylaxis

   • George H. Caughey

   Pages 89-105

8. Aspirin and NSAID Reactions: Diagnosis, Pathophysiology, and Management

   • Andrew A. White, Tanya M. Laidlaw, Katharine Woessner

   Pages 107-125

9. IgE-Dependent and Independent Effector Mechanisms in Human and Murine Anaphylaxis

   • Fred D. Finkelman

   Pages 127-144

10. Food-Induced Anaphylaxis

    • Kirsi M. Järvinen-Seppo, Anna Nowak-Węgrzyn

    Pages 145-169

11. Antibiotic-Induced Anaphylaxis

    • Pascal Demoly, Philippe Jean Bousquet, Antonino Romano

    Pages 171-182

12. Anaphylaxis During Radiological Procedures and in the Peri-operative Setting

    • Pascale Dewachter, David L. Hepner

    Pages 183-208

13. Hymenoptera-Induced Hypersensitivity Reactions and Anaphylaxis

    • Mitja Kosnik, Peter Korosec

    Pages 209-222

14. Idiopathic Anaphylaxis

    • Karen Hsu Blatman, Leslie C. Grammer

    Pages 223-234

15. Exercise-Induced Anaphylaxis and Food-Dependent Exercise-Induced Anaphylaxis

    • Anna M. Feldweg, Albert L. Sheffer

    Pages 235-243

16. Mastocytosis and Mast Cell Activation Syndromes Presenting as Anaphylaxis

    • Cem Akin, Dean D. Metcalfe

    Pages 245-256

17. Anaphylaxis in Mastocytosis

    • Luis Escribano, Alberto Orfao

    Pages 257-269

18. Flushing and Urticarial Syndromes Presenting as Anaphylaxis

    • Joseph H. Butterfield

    Pages 271-284

19. Pharmacologic Management of Acute Anaphylaxis

    • David I. Bernstein

    Pages 285-295

20. Drug Desensitizations in the Management of Allergy and Anaphylaxis to Chemotherapeutic Agents and Monoclonal Antibodies

    • Aleena Banerji, Patrick Brennan, Paul Hesterberg, Eyal Oren, F. Ida Hsu

    Pages 297-311

Despite wide recognition as a serious public health problem, anaphylaxis and hypersensitivity reactions remain under-recognized and under-diagnosed. This book fills the gaps in our understanding of the identification of triggers, recognition of clinical presentations, understanding of the natural history of these reactions, and selection of treatment strategies including those focused on cellular and molecular targets. The book provides a detailed examination of disease etiology, pathogenesis, and pathophysiology and their correlation to clinical practice. Forefront knowledge of the mediators and mechanisms of anaphylaxis is covered with an emphasis on how new discoveries shape our current and emerging therapies.

• Allergy
• Anaphylaxis
• Angioedema
• Hypersensitivity
• Immunology
• Peanut
• Uticaria

From the reviews:

“Presents a detailed look at the current state of knowledge on anaphylaxis and hypersensitivity reactions. … achieves its objectives in a very readable fashion. The book is meant for clinicians of all types, translational researchers, and basic researchers. … useful for a graduate level course. … quite readable and one could go through the book from cover to cover without losing interest. … packed with useful information about anaphylaxis and hypersensitivity reactions. The material is presented in a clear and readable fashion by experts.” (Marion C. Cohen, Doody’s Review Service, June, 2011)

• Harvard Medical School, Ambulatory Center, Brigham and Women’s Hospital, Chestnut Hill, USA

  Mariana C. Castells

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