Overview
- Relies heavily on new knowledge
- The use of knock-out mice and subtype-selective drugs merit discussion in stand-alone chapters
- The field of G protein-coupled receptors has advanced significantly since the publication of the first edition, with a model of GPCR signaling based on linear, compartmentalized pathways having been replaced by a more complex, richer model in which neurotransmitter effects are mediated by a signalplex composed of numerous signaling proteins, including multiple GPCRs, other types of receptors, such as ionotropic receptors, accessory and scaffolding proteins, and effectors
- Key aspects of this advanced model are specifically addressed in new chapters on dopamine receptor-interacting proteins and on dopamine receptor oligomerization
- Includes supplementary material: sn.pub/extras
Part of the book series: The Receptors (REC)
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Table of contents (19 chapters)
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Front Matter
Keywords
About this book
As sites of action for drugs used to treat schizophrenia and Parkinson’s disease, dopamine receptors are among the most validated drug targets for neuropsychiatric disorders. Dopamine receptors are also drug targets or potential targets for other disorders such as substance abuse, depression, Tourette’s syndrome, and attention deficit hyperactivity disorder. Updated from the successful first edition, "The Dopamine Receptors" serves as a reference work on dopamine receptors while also highlighting the areas of research that are most active today. To achieve this goal, authors have written chapters that set a broad area of research in its historical context, rather than focusing on the research output of their own laboratories.
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Editors and Affiliations
Bibliographic Information
Book Title: The Dopamine Receptors
Editors: Kim A. Neve
Series Title: The Receptors
DOI: https://doi.org/10.1007/978-1-60327-333-6
Publisher: Humana Totowa, NJ
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Humana Press 2010
Hardcover ISBN: 978-1-60327-332-9Published: 05 November 2009
Softcover ISBN: 978-1-61779-656-2Published: 25 February 2012
eBook ISBN: 978-1-60327-333-6Published: 01 December 2009
Series ISSN: 1048-6909
Series E-ISSN: 2524-6488
Edition Number: 2
Number of Pages: XII, 648
Number of Illustrations: 63 b/w illustrations, 6 illustrations in colour
Topics: Neurology, Neurosciences, Pharmacology/Toxicology, Neurobiology, Human Physiology, Pharmaceutical Sciences/Technology