Editors:
- This book will focus on telomere and telomerase in human cancers and may provide medical doctors, pathologists, and translational cancer researchers with a deep understanding of these unique and fascinating molecules, as well as hot topics in clinical applications
Part of the book series: Cancer Drug Discovery and Development (CDD&D)
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Table of contents (16 chapters)
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Front Matter
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Basic Background
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Telomeres and Telomerase in Human Cancers
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Back Matter
About this book
Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985. In 1990s, it was proven that this enzyme also plays a key role in the infinite proliferation of human cancer cells. Now telomere and telomerase are widely accepted as important factors involved in cancer biology, and as promising diagnostic tools and therapeutic targets. Recently, role of telomerase in “cancer stem cells” has become another attractive story. Until now, there are several good books on telomere and telomerase focusing on biology in ciliates, yeasts, and mouse or basic sciences in human, providing basic scientists or students with updated knowledge.
Editors and Affiliations
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Dept. Translational Cancer Research, Hiroshima University, Hiroshima, Japan
Keiko Hiyama
Bibliographic Information
Book Title: Telomeres and Telomerase in Cancer
Editors: Keiko Hiyama
Series Title: Cancer Drug Discovery and Development
DOI: https://doi.org/10.1007/978-1-60327-879-9
Publisher: Humana Totowa, NJ
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Humana Press 2009
Hardcover ISBN: 978-1-60327-306-0Published: 27 February 2009
Softcover ISBN: 978-1-61737-888-1Published: 19 November 2010
eBook ISBN: 978-1-60327-879-9Published: 18 March 2009
Series ISSN: 2196-9906
Series E-ISSN: 2196-9914
Edition Number: 1
Number of Pages: XII, 380
Number of Illustrations: 41 b/w illustrations, 19 illustrations in colour
Topics: Cancer Research, Oncology, Pharmacology/Toxicology